Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 6 0 1995 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		interleukin 1 beta 0.276 0.962 0.13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 3 0 2009 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT 		glutamic--pyruvic transaminase 0.403 0.923 3.6E-19
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 3 0 1977 2016
Entrez Id: 2936
Gene Symbol: GSR
GSR 		glutathione-disulfide reductase 0.494 0.846 1.3E-06
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2013 2017
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2003 2018
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		nuclear receptor subfamily 1 group H member 4 0.513 0.808 9.4E-04
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 2 0 2003 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2007 2011
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2008 2013
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		actin beta 0.325 0.923 0.99
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2012 2015
Entrez Id: 7450
Gene Symbol: VWF
VWF 		von Willebrand factor 0.408 0.885 3.2E-25
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 1995 2017
Entrez Id: 350
Gene Symbol: APOH
APOH 		apolipoprotein H 0.563 0.769 1.6E-15
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2005 2013
Entrez Id: 847
Gene Symbol: CAT
CAT 		catalase 0.359 0.962 1.6E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2011 2015
Entrez Id: 5428
Gene Symbol: POLG
POLG 		DNA polymerase gamma, catalytic subunit 0.457 0.846 2.1E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2008 2014
Entrez Id: 2729
Gene Symbol: GCLC
GCLC 		glutamate-cysteine ligase catalytic subunit 0.509 0.885 0.43
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2007 2009
Entrez Id: 8772
Gene Symbol: FADD
FADD 		Fas associated via death domain 0.537 0.846 0.53
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 2 0 2015 2016
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		hepcidin antimicrobial peptide 0.433 0.846 8.2E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 572
Gene Symbol: BAD
BAD 		BCL2 associated agonist of cell death 0.553 0.769 4.6E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2016 2016
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		serpin family A member 1 0.410 0.923 6.8E-08
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2000 2000
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		toll like receptor 4 0.321 0.962 4.6E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 6554
Gene Symbol: SLC10A1
SLC10A1 		solute carrier family 10 member 1 0.626 0.462 4.8E-16
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2017 2017
Entrez Id: 81285
Gene Symbol: OR51E2
OR51E2 		olfactory receptor family 51 subfamily E member 2 0.751 0.192 1.5E-04
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 831
Gene Symbol: CAST
CAST 		calpastatin 0.541 0.846 4.1E-12
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2006 2006
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		caspase 8 0.404 0.923 3.7E-06
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2016 2016
Entrez Id: 84706
Gene Symbol: GPT2
GPT2 		glutamic--pyruvic transaminase 2 0.650 0.577 3.4E-04
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 9478
Gene Symbol: CABP1
CABP1 		calcium binding protein 1 0.805 0.231 0.89
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.200 None 1.000 1 0 2011 2011