Source: GENOMICS_ENGLAND

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 361
Gene Symbol: AQP4
AQP4
aquaporin 4 0.525 0.793 2.8E-03
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 8 0 1998 2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.347 0.897 1.0E-03
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 6 0 2003 2017
Entrez Id: 1690
Gene Symbol: COCH
COCH
cochlin 0.735 0.172 1.6E-07
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 strong 6 0 1998 2017
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
protein kinase C beta 0.564 0.690 1.00
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 moderate 3 0 2015 2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
nuclear factor kappa B subunit 1 0.365 0.931 1.00
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 3 0 2015 2017
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A
calcium voltage-gated channel subunit alpha1 A 0.534 0.552 1.00
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 3 0 1996 2017
Entrez Id: 84908
Gene Symbol: FAM136A
FAM136A
family with sequence similarity 136 member A 0.928 0.034 5.4E-04
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 moderate 2 0 2015 2017
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
protein tyrosine phosphatase, non-receptor type 22 0.497 0.793 3.6E-19
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 2 0 2010 2017
Entrez Id: 223117
Gene Symbol: SEMA3D
SEMA3D
semaphorin 3D 0.713 0.345 8.8E-08
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 2 0 2017 2018
Entrez Id: 1837
Gene Symbol: DTNA
DTNA
dystrobrevin alpha 0.696 0.241 0.69
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 moderate 2 0 2015 2017
Entrez Id: 1805
Gene Symbol: DPT
DPT
dermatopontin 0.696 0.517 5.5E-06
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 moderate 2 0 2017 2018
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3
POU class 4 homeobox 3 0.752 0.414 0.93
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 5445
Gene Symbol: PON2
PON2
paraoxonase 2 0.596 0.621 6.1E-05
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.443 0.828 9.0E-11
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 5970
Gene Symbol: RELA
RELA
RELA proto-oncogene, NF-kB subunit 0.456 0.828 1.00
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 6183
Gene Symbol: MRPS12
MRPS12
mitochondrial ribosomal protein S12 1.000 0.034 2.3E-04
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.353 0.897 0.62
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 6351
Gene Symbol: CCL4
CCL4
C-C motif chemokine ligand 4 0.526 0.862 0.21
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 5172
Gene Symbol: SLC26A4
SLC26A4
solute carrier family 26 member 4 0.554 0.759 1.4E-21
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 4883
Gene Symbol: NPR3
NPR3
natriuretic peptide receptor 3 0.727 0.414 1.1E-05
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
melatonin receptor 1B 0.642 0.586 7.7E-04
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 4548
Gene Symbol: MTR
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase 0.493 0.724 2.6E-10
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.510 0.655 1.8E-14
CUI: C4302111
Disease: Familial Ménière disease
Familial Ménière disease
disease 0.300 limited 1 0 2017 2017