Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD A critical role of SRC-suppressed C kinase substrate in rat astrocytes after chronic constriction injury. 19937403

2010

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. 2493483

1989

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. 2493483

1989

Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves. 19909480

2009

Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves. 19909480

2009

Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Alterations in the expression of ATP-sensitive potassium channel subunit mRNA after acute peripheral nerve and spinal cord injury. 17108688

2007

Entrez Id: 386724
Gene Symbol: AMIGO3
AMIGO3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD AMIGO3 is an NgR1/p75 co-receptor signalling axon growth inhibition in the acute phase of adult central nervous system injury. 23613963

2013

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Application of angiotensin II to healthy rat sciatic nerve can produce neuropathy without associated vasculopathy. 20886512

2010

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors. 11240015

2001

Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors. 11240015

2001

Entrez Id: 4622
Gene Symbol: MYH4
MYH4
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury. 14973145

2004

Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord. 17720801

2008

Entrez Id: 5111
Gene Symbol: PCNA
PCNA
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Changes in CLIP3 expression after sciatic nerve injury in adult rats. 23014974

2012

Entrez Id: 9722
Gene Symbol: NOS1AP
NOS1AP
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Changes in mRNA for CAPON and Dexras1 in adult rat following sciatic nerve transection. 17768032

2008

Entrez Id: 5376
Gene Symbol: PMP22
PMP22
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13). 1556154

1992

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Chinese tuina downregulates the elevated levels of tissue plasminogen activator in sciatic nerve injured Sprague-Dawley rats. 25967608

2017

Entrez Id: 4922
Gene Symbol: NTS
NTS
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Chronic pain increases brainstem proneurotensin/neuromedin-N mRNA expression: a hybridization-histochemical and immunohistochemical study using three different rat models for chronic nociception. 8518953

1993

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Complement activation contributes to leukocyte recruitment and neuropathic pain following peripheral nerve injury in rats. 18052971

2007

Entrez Id: 1269
Gene Symbol: CNR2
CNR2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833. 19345493

2009

Entrez Id: 5764
Gene Symbol: PTN
PTN
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Different pattern of pleiotrophin and midkine expression in neuropathic pain: correlation between changes in pleiotrophin gene expression and rat strain differences in neuropathic pain. 18365878

2008

Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens. 23835161

2013

Entrez Id: 246213
Gene Symbol: SLC17A8
SLC17A8
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens. 23835161

2013

Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Distribution and regulation of L-type calcium channels in deep dorsal horn neurons after sciatic nerve injury in rats. 16026470

2005

Entrez Id: 57555
Gene Symbol: NLGN2
NLGN2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Down-regulation of mRNAs for synaptic adhesion molecules neuroligin-2 and -3 and synCAM1 in spinal motoneurons after axotomy. 17492651

2007

Entrez Id: 54413
Gene Symbol: NLGN3
NLGN3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Down-regulation of mRNAs for synaptic adhesion molecules neuroligin-2 and -3 and synCAM1 in spinal motoneurons after axotomy. 17492651

2007