×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Marked increased expression of cyclooxygenase 2 (COX-2 ), a prostaglandin-synthesizing enzyme that is pharmacologically inhibited by nonsteroid anti-inflammatory-type drugs, is a major early oncogenic event in the genesis of human colon neoplasia .
15574495
2004
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Survivin and Cyclooxygenase-2 are co-expressed in human and mouse colon carcinoma and in terminally differentiated colonocytes.
17128412
2007
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
Biomarker
LHGDN
The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer.
16203768
2005
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.
19088039
2008
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.
11705852
2001
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.
12839952
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2.
12767532
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
Biomarker
LHGDN
Induction of cyclooxygenase-2 in monocyte/macrophage by mucins secreted from colon cancer cells.
12598658
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
Biomarker
LHGDN
RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility.
17178865
2006
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
Biomarker
LHGDN
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
12124799
2002
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
Biomarker
LHGDN
Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
18326857
2008
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a.
14675489
2003
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
Colonic Neoplasms
0.600
AlteredExpression
LHGDN
Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways.
15896711
2005