Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Biomarker MGD

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Biomarker MGD

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.570 Biomarker MGD

Entrez Id: 811
Gene Symbol: CALR
CALR
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker MGD

Entrez Id: 8048
Gene Symbol: CSRP3
CSRP3
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker MGD

Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker MGD

Entrez Id: 136319
Gene Symbol: MTPN
MTPN
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.270 Biomarker MGD

Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.230 Biomarker MGD

Entrez Id: 5469
Gene Symbol: MED1
MED1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 Biomarker MGD

Entrez Id: 4879
Gene Symbol: NPPB
NPPB
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Biomarker RGD Increased plasma levels and blunted effects of brain natriuretic peptide in rats with congestive heart failure. 1831369

1991
Entrez Id: 1889
Gene Symbol: ECE1
ECE1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.210 Biomarker RGD Renal endothelin-converting enzyme in rats with congestive heart failure. 9595392

1998
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Biomarker RGD Importantly, cardiac dysfunction was preceded by elevated betaARK1 levels and activity, thus suggesting that betaARK1 may be a precipitating factor in the transition from hypertension-induced compensatory cardiac hypertrophy to HF. 9931137

1999
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Biomarker RGD Expression of endothelin-1, ETA and ETB receptors, and ECE and distribution of endothelin-1 in failing rat heart. 10199843

1999
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker RGD Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors. 10421602

1999
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.210 Biomarker RGD Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors. 10421602

1999
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.290 Biomarker RGD MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. 10773234

2000
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.240 Biomarker RGD MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. 10773234

2000
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker RGD MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. 10773234

2000
Entrez Id: 7079
Gene Symbol: TIMP4
TIMP4
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker RGD MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. 10773234

2000
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 Biomarker RGD MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition. 10773234

2000
Entrez Id: 4317
Gene Symbol: MMP8
MMP8
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 ModifyingMutation RGD MMP-8 and MMP-14 protein levels increased later during heart failure progression. 10773235

2000
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 ModifyingMutation RGD MMP-8 and MMP-14 protein levels increased later during heart failure progression. 10773235

2000
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 ModifyingMutation RGD Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat. 10773235

2000
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.600 Therapeutic RGD Tumor necrosis factor-alpha (TNF-alpha) probably affects the pathogenesis of heart failure. 11668085

2001
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker RGD Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure. 11342481

2001