| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.985 | 268 | 3 | 1985 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.800 | None | 0.978 | 135 | 11 | 1991 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.991 | 112 | 0 | 1986 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.600 | None | 0.979 | 95 | 3 | 1995 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.800 | None | 0.988 | 83 | 5 | 1996 | 2019 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.600 | None | 1.000 | 79 | 0 | 1996 | 2020 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.400 | None | 0.986 | 69 | 2 | 2003 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 1.000 | 64 | 0 | 1997 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 62 | 2 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 57 | 0 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 55 | 2 | 2003 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.963 | 54 | 0 | 1999 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 52 | 1 | 2003 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 52 | 0 | 2003 | 2020 | ||||||||
|
MIA SH3 domain containing | 0.537 | 0.769 | 1.7E-05 |
|
disease | 0.100 | None | 1.000 | 48 | 0 | 1991 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.976 | 41 | 0 | 2002 | 2020 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.100 | None | 1.000 | 41 | 0 | 2014 | 2020 | ||||||||
|
mucin 1, cell surface associated | 0.384 | 0.885 | 1.9E-02 |
|
disease | 0.100 | None | 1.000 | 41 | 2 | 1994 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 39 | 0 | 2003 | 2019 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.600 | None | 1.000 | 38 | 1 | 1997 | 2020 | ||||||||
|
mesothelin | 0.525 | 0.692 | 5.9E-25 |
|
disease | 0.400 | None | 0.943 | 35 | 0 | 2001 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.100 | None | 1.000 | 35 | 1 | 2003 | 2020 | ||||||||
|
EPH receptor B2 | 0.374 | 0.846 | 1.00 |
|
disease | 0.100 | None | 1.000 | 33 | 0 | 2008 | 2019 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.100 | None | 0.970 | 33 | 0 | 1998 | 2019 | ||||||||
|
TNF superfamily member 10 | 0.413 | 0.885 | 0.13 |
|
disease | 0.400 | None | 1.000 | 33 | 0 | 2001 | 2019 |