|
rs401681
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
A small number of common susceptibility loci have been identified for pancreatic cancer, one of which is marked by rs401681 in the TERT-CLPTM1L gene region on chromosome 5p15.33.
|
25940397 |
2015 |
|
rs401681
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that T allele of CLPTM1L-telomerase reverse transcriptase rs401681 polymorphism is associated with an increased PC risk, especially among Chinese.
|
25284078 |
2015 |
|
rs401681
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
Our data suggests that the T allele of rs401681 in CLPTM1L-TERT locus predisposes its carriers to pancreatic cancer, and further research into the function of CLPTM1L-TERT locus and its potential biological mechanism association may be warranted.
|
24577890 |
2014 |
|
rs401681
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
These findings suggested that rs401681 C allele was a low-penetrance risk allele for the development of cancers of lung, bladder, prostate and basal cell carcinoma, but a potential protective allele for melanoma and pancreatic cancer.
|
23226346 |
2012 |
|
rs401681
|
|
Malignant neoplasm of pancreas
|
T |
0.740 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
|
20101243 |
2010 |
|
rs505922
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
This study provided evidence of SNP rs505922 C allele as a strong risk factor of cancer susceptibility, specifically for pancreatic cancer.
|
25656610 |
2015 |
|
rs505922
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
SNP rs505922, located within the first intron of the ABO gene, has been associated with the adenocarcinoma subtype of pancreatic cancer.
|
22642827 |
2012 |
|
rs505922
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
Consistent with earlier reports showing a higher risk of PC for individuals with the non-O blood type, the previously reported protective allele (T) for rs505922 was found to be strongly correlated (r(2) = 0.96) with the O allele.
|
21306478 |
2011 |
|
rs505922
|
|
Malignant neoplasm of pancreas
|
C |
0.740 |
GeneticVariation
|
GWASDB |
We identified an association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 (combined P = 5.37 x 10(-8); multiplicative per-allele odds ratio 1.20; 95% confidence interval 1.12-1.28).
|
19648918 |
2009 |
|
rs505922
|
|
Malignant neoplasm of pancreas
|
|
0.740 |
GeneticVariation
|
BEFREE |
We identified an association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 (combined P = 5.37 x 10(-8); multiplicative per-allele odds ratio 1.20; 95% confidence interval 1.12-1.28).
|
19648918 |
2009 |
|
rs3790844
|
|
Malignant neoplasm of pancreas
|
|
0.730 |
GeneticVariation
|
BEFREE |
Our results showed that the rs3790843 (GA vs GG: OR=0.86, CI=0.76-0.98, <i>P</i>=0.992; GA+AA vs GG: OR=0.83, CI=0.73-0.94, <i>P</i>=0.950; A vs G: OR=0.85, CI=0.78-0.93, <i>P</i>=0.802), rs3790844 (CC vs TT: OR=0.65, CI=0.54-0.78, <i>P</i>=0.617; CC vs TT+CT: OR=0.73, CI=0.62-0.85, <i>P</i>=0.742; C vs T: OR=0.78, CI=0.73-0.84, <i>P</i>=0.555) and rs12029406 (TT vs CC: OR=0.73, CI=0.61-0.89, <i>P</i>=0.483; TT vs CC+CT: OR=0.78, CI=0.66-0.92, <i>P</i>=0.648; T vs C: OR=0.87, CI=0.79-0.95, <i>P</i>=0.837) polymorphisms were associated statistically with the risk of pancreatic cancer.
|
29785120 |
2018 |
|
rs3790844
|
|
Malignant neoplasm of pancreas
|
|
0.730 |
GeneticVariation
|
BEFREE |
In previously reported pancreatic cancer-associated SNPs, rs3790844 (NR5A2) showed a significant correlation with PDAC in our cohort.
|
28639428 |
2018 |
|
rs3790844
|
|
Malignant neoplasm of pancreas
|
|
0.730 |
GeneticVariation
|
BEFREE |
Our case-control study found that rs3790843 and rs3790844 in the NR5A2 gene are associated with pancreatic cancer risk in Japanese subjects.
|
26592175 |
2015 |
|
rs3790844
|
|
Malignant neoplasm of pancreas
|
T |
0.730 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
|
20101243 |
2010 |
|
rs10500715
|
|
Malignant neoplasm of pancreas
|
T |
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of survival in patients with pancreatic adenocarcinoma.
|
23180869 |
2014 |
|
rs1153280
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |
|
rs1153287
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |
|
rs1153294
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |
|
rs117214
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |
|
rs12362504
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of survival in patients with pancreatic adenocarcinoma.
|
23180869 |
2014 |
|
rs12413624
|
|
Malignant neoplasm of pancreas
|
T |
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |
|
rs12456874
|
|
Malignant neoplasm of pancreas
|
G |
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of survival in patients with pancreatic adenocarcinoma.
|
23180869 |
2014 |
|
rs1447826
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Including additional controls from public databases improves the power of a genome-wide association study.
|
21849791 |
2011 |
|
rs1455311
|
|
Malignant neoplasm of pancreas
|
|
0.700 |
GeneticVariation
|
GWASDB |
Including additional controls from public databases improves the power of a genome-wide association study.
|
21849791 |
2011 |
|
rs1547374
|
|
Malignant neoplasm of pancreas
|
A |
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.
|
22158540 |
2011 |