| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
phenotype | 0.400 | None | 0.956 | 44 | 4 | 1993 | 2020 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 1993 | 2001 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 1993 | 2015 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
phenotype | 0.200 | None | 0.944 | 283 | 3 | 1995 | 2020 | ||||||||
|
serpin family A member 3 | 0.486 | 0.846 | 8.8E-14 |
|
phenotype | 0.050 | None | 1.000 | 5 | 0 | 1996 | 2008 | ||||||||
|
N-acetyl-alpha-glucosaminidase | 0.546 | 0.769 | 1.4E-08 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 1996 | 1996 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 1996 | 1996 | ||||||||
|
cystatin B | 0.530 | 0.692 | 6.6E-03 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 1997 | 1997 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
phenotype | 0.200 | None | 1.000 | 14 | 4 | 1998 | 2019 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
phenotype | 0.030 | None | 1.000 | 3 | 1 | 1998 | 2017 | ||||||||
|
tripeptidyl peptidase 1 | 0.551 | 0.808 | 6.3E-07 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 1998 | 1998 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
phenotype | 0.050 | None | 1.000 | 5 | 1 | 1999 | 2019 | ||||||||
|
TATA-box binding protein | 0.552 | 0.846 | 1.5E-02 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 1999 | 1999 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
phenotype | 0.100 | None | 0.909 | 11 | 1 | 2000 | 2019 | ||||||||
|
spastin | 0.579 | 0.577 | 1.00 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2000 | 2009 | ||||||||
|
synaptophysin | 0.481 | 0.808 | 0.92 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2000 | 2018 | ||||||||
|
myelin protein zero like 2 | 0.653 | 0.500 | 1.1E-12 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2000 | 2000 | ||||||||
|
solute carrier family 26 member 4 | 0.507 | 0.885 | 9.0E-22 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2000 | 2000 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
phenotype | 0.200 | None | 0.964 | 28 | 1 | 2002 | 2020 | ||||||||
|
FMRP translational regulator 1 | 0.473 | 0.769 | 0.65 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2011 | ||||||||
|
CLN6 transmembrane ER protein | 0.670 | 0.231 | 1.0E-04 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
twinkle mtDNA helicase | 0.516 | 0.692 | 3.2E-03 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
ATXN8 opposite strand lncRNA | 0.650 | 0.423 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | |||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.100 | None | 0.857 | 14 | 0 | 2003 | 2019 | ||||||||
|
butyrylcholinesterase | 0.447 | 0.923 | 1.1E-13 |
|
phenotype | 0.100 | None | 1.000 | 12 | 2 | 2003 | 2019 |