| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
phenotype | 0.400 | None | 0.956 | 44 | 4 | 1993 | 2020 | ||||||||
|
clusterin | 0.426 | 0.885 | 7.8E-05 |
|
phenotype | 0.350 | None | 1.000 | 5 | 1 | 2011 | 2018 | ||||||||
|
phosphatidylinositol binding clathrin assembly protein | 0.592 | 0.538 | 1.00 |
|
phenotype | 0.330 | None | 1.000 | 3 | 0 | 2011 | 2018 | ||||||||
|
sortilin related receptor 1 | 0.582 | 0.692 | 7.7E-11 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2018 | ||||||||
|
calcium voltage-gated channel subunit alpha1 C | 0.510 | 0.846 | 1.00 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
bridging integrator 1 | 0.550 | 0.692 | 0.78 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2018 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
phenotype | 0.200 | None | 0.944 | 283 | 3 | 1995 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
phenotype | 0.200 | None | 0.964 | 28 | 1 | 2002 | 2020 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
phenotype | 0.200 | None | 0.938 | 16 | 1 | 2004 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
phenotype | 0.200 | None | 1.000 | 14 | 4 | 1998 | 2019 | ||||||||
|
translocase of outer mitochondrial membrane 40 | 0.590 | 0.538 | 0.99 |
|
phenotype | 0.130 | None | 1.000 | 3 | 3 | 2014 | 2017 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
phenotype | 0.130 | None | 1.000 | 3 | 0 | 2003 | 2015 | ||||||||
|
eukaryotic translation elongation factor 1 alpha 2 | 0.554 | 0.808 | 1.00 |
|
phenotype | 0.120 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
synaptojanin 1 | 0.576 | 0.577 | 0.43 |
|
phenotype | 0.120 | None | 1.000 | 2 | 1 | 2015 | 2018 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
phenotype | 0.120 | None | 1.000 | 2 | 0 | 2008 | 2009 | ||||||||
|
chromosome 19 open reading frame 12 | 0.641 | 0.615 | 0.34 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
TATA-box binding protein | 0.552 | 0.846 | 1.5E-02 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 1999 | 1999 | ||||||||
|
sequestosome 1 | 0.428 | 0.885 | 8.6E-04 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
arylsulfatase A | 0.448 | 0.923 | 1.1E-11 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
TANK binding kinase 1 | 0.513 | 0.846 | 7.5E-02 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
calcium voltage-gated channel subunit alpha1 A | 0.489 | 0.769 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||||||
|
phospholipase A2 group VI | 0.476 | 0.846 | 2.5E-10 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
SPG11 vesicle trafficking associated, spatacsin | 0.576 | 0.538 | 1.6E-39 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2009 | 2010 | ||||||||
|
sodium voltage-gated channel alpha subunit 1 | 0.477 | 0.808 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
solute carrier family 1 member 2 | 0.511 | 0.731 | 0.71 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 |