| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 1.000 | strong | 0.956 | 22 | 88 | 1992 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 1.000 | strong | 0.951 | 24 | 69 | 1994 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 1.000 | None | 0.985 | 1 | 6 | 2001 | 2020 | ||||||||
|
zinc finger protein 668 | 0.760 | 0.154 | 2.9E-04 |
|
disease | 0.310 | None | 1.000 | 0 | 3 | 2011 | 2011 | ||||||||
|
myosin heavy chain 1 | 0.805 | 0.500 | 1.4E-56 |
|
disease | 0.300 | None | 0 | 3 | |||||||||||
|
cubilin | 0.587 | 0.769 | 4.6E-42 |
|
disease | 0.300 | None | 0 | 3 | |||||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.800 | None | 0.951 | 2 | 2 | 2001 | 2020 | ||||||||
|
exocyst complex component 3 like 1 | 1.000 | 0.077 | 1.7E-19 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
roundabout guidance receptor 1 | 0.535 | 0.731 | 7.3E-16 |
|
disease | 0.330 | None | 1.000 | 0 | 2 | 2002 | 2019 | ||||||||
|
deoxyribonuclease 1 like 3 | 0.575 | 0.769 | 3.0E-05 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
THO complex 5 | 0.769 | 0.308 | 4.5E-02 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
MAM domain containing 4 | 0.931 | 0.115 | 1.4E-51 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
prohibitin | 0.511 | 0.846 | 0.76 |
|
disease | 0.600 | None | 0.944 | 0 | 2 | 1994 | 2018 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.800 | limited | 1.000 | 0 | 2 | 1991 | 2019 | ||||||||
|
proline rich coiled-coil 2A | 0.656 | 0.654 | 1.00 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
collagen type XIX alpha 1 chain | 0.890 | 0.154 | 4.8E-33 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.600 | None | 0.947 | 0 | 2 | 1990 | 2020 | ||||||||
|
ectopic P-granules autophagy protein 5 homolog | 0.623 | 0.769 | 1.4E-13 |
|
disease | 0.310 | None | 1.000 | 0 | 2 | 2007 | 2007 | ||||||||
|
myogenic differentiation 1 | 0.569 | 0.654 | 0.15 |
|
disease | 0.340 | None | 1.000 | 0 | 2 | 1988 | 2017 | ||||||||
|
fukutin | 0.511 | 0.692 | 8.7E-07 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
SIX homeobox 4 | 0.792 | 0.192 | 0.69 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
cyclic nucleotide gated channel subunit alpha 2 | 0.931 | 0.154 | 9.8E-04 |
|
disease | 0.300 | None | 0 | 2 | |||||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.800 | None | 0.963 | 3 | 1 | 2001 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.800 | None | 0.970 | 3 | 1 | 2006 | 2020 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.600 | None | 0.957 | 2 | 1 | 1997 | 2019 |