×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Brain Ischemia
0.210
Therapeutic
RGD
Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus.
15585409 2005
×
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
Brain Ischemia
0.210
Biomarker
RGD
SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model.
18206136 2008
×
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
Brain Ischemia
0.210
Biomarker
RGD
Subtype activation and interaction of protein kinase C and mitogen-activated protein kinase controlling receptor expression in cerebral arteries and microvessels after subarachnoid hemorrhage.
18032736 2008
×
Entrez Id: 6547
Gene Symbol: SLC8A3
SLC8A3
Brain Ischemia
0.210
Biomarker
RGD
Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions.
16107787 2006
×
Entrez Id: 4891
Gene Symbol: SLC11A2
SLC11A2
Brain Ischemia
0.210
Biomarker
RGD
Tanshinone IIA prevented brain iron dyshomeostasis in cerebral ischemic rats.
21325818 2011
×
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Brain Ischemia
0.210
Biomarker
RGD
RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats.
19574998 2009
×
Entrez Id: 54207
Gene Symbol: KCNK10
KCNK10
Brain Ischemia
0.210
Biomarker
RGD
Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia.
15652517 2005
×
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
Brain Ischemia
0.210
Biomarker
RGD
Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia.
14741413 2004
×
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Brain Ischemia
0.210
Biomarker
RGD
Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death.
17936001 2008
×
Entrez Id: 718
Gene Symbol: C3
C3
Brain Ischemia
0.210
Biomarker
RGD
Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats.
14561876 2003
×
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
Brain Ischemia
0.210
Biomarker
RGD
Cloning of rat HIV-1-chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain.
9670989 1998
×
Entrez Id: 7276
Gene Symbol: TTR
TTR
Brain Ischemia
0.210
Biomarker
RGD
Combined proteomic approach with SELDI-TOF-MS and peptide mass fingerprinting identified the rapid increase of monomeric transthyretin in rat cerebrospinal fluid after transient focal cerebral ischemia.
15469881 2004
×
Entrez Id: 6543
Gene Symbol: SLC8A2
SLC8A2
Brain Ischemia
0.210
Biomarker
RGD
Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions.
16107787 2006
×
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
Brain Ischemia
0.210
Therapeutic
RGD
Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat.
23644141 2013
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Brain Ischemia
0.210
Biomarker
RGD
Early and sharp nitric oxide production and anoxic depolarization in the rat hippocampus during transient forebrain ischemia.
17451676 2007
×
Entrez Id: 1020
Gene Symbol: CDK5
CDK5
Brain Ischemia
0.210
Biomarker
RGD
Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors.
14502288 2003
×
Entrez Id: 1191
Gene Symbol: CLU
CLU
Brain Ischemia
0.210
Biomarker
RGD
Delayed, but prolonged increases in astrocytic clusterin (ApoJ) mRNA expression following acute cortical spreading depression in the rat: evidence for a role of clusterin in ischemic tolerance.
12782389 2003
×
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
Brain Ischemia
0.210
Biomarker
RGD
Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats.
20204486 2010
×
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
Brain Ischemia
0.210
Biomarker
RGD
The effect of recombinant human erythropoietin on neurovasculature repair after focal ischemic stroke in neonatal rats.
17494864 2007
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Brain Ischemia
0.200
Biomarker
RGD
Lesion-associated expression of transforming growth factor-beta-2 in the rat nervous system: evidence for down-regulating the phagocytic activity of microglia and macrophages.
14997937 2004
×
Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
Brain Ischemia
0.200
Biomarker
RGD
Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats.
12150772 2002
×
Entrez Id: 831
Gene Symbol: CAST
CAST
Brain Ischemia
0.200
Biomarker
RGD
3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydro-chloride 3.5 hydrate (DY-9760e) is neuroprotective in rat microsphere embolism: role of the cross-talk between calpain and caspase-3 through calpastatin.
16467455 2006
×
Entrez Id: 2149
Gene Symbol: F2R
F2R
Brain Ischemia
0.200
Biomarker
RGD
Taken together, these data suggest involvement of the thrombin receptors PAR-1 , PAR-3, and PAR-4 in the pathophysiology of brain ischemia .
14705148 2004
×
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
Brain Ischemia
0.200
Biomarker
RGD
DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo.
17350602 2007
×
Entrez Id: 1075
Gene Symbol: CTSC
CTSC
Brain Ischemia
0.200
Biomarker
RGD
Genomics of the periinfarction cortex after focal cerebral ischemia.
12843783 2003