| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
serine hydroxymethyltransferase 1 | 0.566 | 0.654 | 1.3E-14 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2014 | 2014 | ||||||||
|
tescalcin | 0.570 | 0.692 | 0.11 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2006 | 2006 | ||||||||
|
CSAG family member 2 | 0.691 | 0.346 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2007 | 2007 | |||||||||
|
ring finger protein 43 | 0.584 | 0.577 | 0.73 |
|
disease | 0.310 | None | < 0.001 | 1 | 0 | 2013 | 2013 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.320 | None | 0.500 | 2 | 0 | 2003 | 2004 | ||||||||
|
RAD51 paralog D | 0.674 | 0.385 | 1.1E-09 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2012 | 2012 | ||||||||
|
cyclin dependent kinase inhibitor 1A | 0.403 | 0.769 | 1.9E-03 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1996 | 2003 | ||||||||
|
solute carrier family 12 member 9 | 0.454 | 0.769 | 1.2E-15 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1996 | 2003 | ||||||||
|
colony stimulating factor 3 | 0.377 | 0.885 | 0.38 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2001 | 2004 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2017 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2006 | 2015 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 2001 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 1991 | 2017 | ||||||||
|
NME/NM23 nucleoside diphosphate kinase 1 | 0.443 | 0.808 | 3.2E-03 |
|
disease | 0.050 | None | 0.800 | 5 | 0 | 1994 | 2013 | ||||||||
|
mucin 16, cell surface associated | 0.479 | 0.808 | 8.3E-112 |
|
disease | 0.100 | None | 0.923 | 13 | 0 | 1993 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.500 | None | 0.947 | 19 | 1 | 1998 | 2018 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.500 | None | 0.978 | 45 | 1 | 1993 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 1.000 | 49 | 0 | 1994 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.400 | None | 1.000 | 18 | 0 | 1989 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1995 | 2015 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1989 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2003 | 2013 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.470 | None | 1.000 | 7 | 0 | 1986 | 2013 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.360 | None | 1.000 | 6 | 0 | 2007 | 2016 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2016 | 2019 |