Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Contractility of ventricular myocytes is well preserved despite altered mechanisms of Ca2+ transport and a changing pattern of mRNA in aged type 2 Zucker diabetic fatty rat heart. 22009485

2012

Entrez Id: 2697
Gene Symbol: GJA1
GJA1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes. 21573906

2011

Entrez Id: 5601
Gene Symbol: MAPK9
MAPK9
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. 21911753

2011

Entrez Id: 9241
Gene Symbol: NOG
NOG
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. 21193740

2011

Entrez Id: 181
Gene Symbol: AGRP
AGRP
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats. 18001323

2007

Entrez Id: 7056
Gene Symbol: THBD
THBD
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Elevation of intracellular cAMP up-regulated thrombomodulin mRNA in cultured vascular endothelial cells derived from spontaneous type-II diabetes mellitus model rat. 17090405

2007

Entrez Id: 6715
Gene Symbol: SRD5A1
SRD5A1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Adrenocortical insufficiency in Otsuka Long-Evans Tokushima Fatty rats, a type 2 diabetes mellitus model. 17884440

2007

Entrez Id: 886
Gene Symbol: CCKAR
CCKAR
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Hyperphagia and obesity in OLETF rats lacking CCK-1 receptors. 16815799

2006

Entrez Id: 9607
Gene Symbol: CARTPT
CARTPT
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD In addition, islet CART expression was examined in two rat models of type 2 diabetes: Goto-Kakizaki (GK) rats and dexamethasone (DEX)-treated rats. 16443761

2006

Entrez Id: 4543
Gene Symbol: MTNR1A
MTNR1A
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status. 16441550

2006

Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto-Kakizaki rat. 16323284

2005

Entrez Id: 51167
Gene Symbol: CYB5R4
CYB5R4
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker MGD Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. 15247412

2004

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Expression of type-1 plasminogen activator inhibitor in the kidney of diabetic rat models. 14693179

2003

Entrez Id: 5507
Gene Symbol: PPP1R3C
PPP1R3C
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker MGD PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. 12727934

2003

Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Vascular proliferation and transforming growth factor-beta expression in pre- and early stage of diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats. 11947899

2002

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Age-related changes in coagulation, fibrinolysis, and platelet aggregation in male WBN/Kob rats. 10899350

2000

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker RGD Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats. 10049703

1999

Entrez Id: 4779
Gene Symbol: NFE2L1
NFE2L1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker MGD

Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Diabetes Mellitus, Non-Insulin-Dependent
0.210 Biomarker MGD

Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Therapeutic RGD Effects of platycodins on liver complications of type 2 diabetes. 25017203

2014

Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Therapeutic RGD Effects of Chinese Fructus Mume formula and its separated prescription extract on insulin resistance in type 2 diabetic rats. 24337852

2013

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Biomarker RGD Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat. 21818837

2012

Entrez Id: 7225
Gene Symbol: TRPC6
TRPC6
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Biomarker RGD Attenuation of store-operated Ca2+ entry and enhanced expression of TRPC channels in caudal artery smooth muscle from Type 2 diabetic Goto-Kakizaki rats. 20337661

2010

Entrez Id: 1641
Gene Symbol: DCX
DCX
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Biomarker RGD Effects of treadmill exercise on cell proliferation and differentiation in the subgranular zone of the dentate gyrus in a rat model of type II diabetes. 18982449

2009

Entrez Id: 4282
Gene Symbol: MIF
MIF
Diabetes Mellitus, Non-Insulin-Dependent
0.220 Biomarker RGD Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. 16571782

2006