| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.800 | strong | 0.985 | 1514 | 24 | 1993 | 2020 | ||||||||
|
C9orf72-SMCR8 complex subunit | 0.496 | 0.769 | 1.1E-06 |
|
disease | 0.800 | limited | 0.985 | 512 | 3 | 2009 | 2020 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.700 | None | 0.979 | 711 | 18 | 2006 | 2020 | ||||||||
|
FUS RNA binding protein | 0.470 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.981 | 308 | 16 | 2009 | 2020 | ||||||||
|
ataxin 2 | 0.482 | 0.808 | 0.85 |
|
disease | 0.700 | None | 0.971 | 67 | 4 | 2006 | 2019 | ||||||||
|
optineurin | 0.548 | 0.808 | 5.9E-18 |
|
disease | 0.700 | None | 0.954 | 63 | 8 | 2010 | 2020 | ||||||||
|
TANK binding kinase 1 | 0.513 | 0.846 | 7.5E-02 |
|
disease | 0.700 | strong | 1.000 | 39 | 2 | 2015 | 2019 | ||||||||
|
sequestosome 1 | 0.428 | 0.885 | 8.6E-04 |
|
disease | 0.700 | None | 0.974 | 36 | 4 | 2009 | 2020 | ||||||||
|
matrin 3 | 0.631 | 0.538 | 1.00 |
|
disease | 0.700 | limited | 1.000 | 20 | 2 | 2009 | 2019 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
disease | 0.700 | None | 0.929 | 13 | 3 | 2007 | 2019 | ||||||||
|
TATA-box binding protein associated factor 15 | 0.626 | 0.500 | 0.17 |
|
disease | 0.700 | limited | 0.929 | 12 | 0 | 2011 | 2019 | ||||||||
|
unc-13 homolog A | 0.705 | 0.423 | 1.00 |
|
disease | 0.700 | None | 1.000 | 11 | 2 | 2009 | 2019 | ||||||||
|
charged multivesicular body protein 2B | 0.543 | 0.731 | 4.6E-06 |
|
disease | 0.680 | None | 1.000 | 8 | 0 | 2006 | 2016 | ||||||||
|
NIMA related kinase 1 | 0.575 | 0.769 | 1.9E-25 |
|
disease | 0.680 | None | 1.000 | 8 | 2 | 2016 | 2019 | ||||||||
|
D-amino acid oxidase | 0.636 | 0.615 | 6.2E-22 |
|
disease | 0.670 | moderate | 1.000 | 7 | 1 | 2010 | 2018 | ||||||||
|
cilia and flagella associated protein 410 | 0.633 | 0.615 | 3.3E-07 |
|
disease | 0.620 | None | 1.000 | 2 | 0 | 2016 | 2019 | ||||||||
|
valosin containing protein | 0.469 | 0.923 | 1.00 |
|
disease | 0.500 | None | 0.962 | 51 | 8 | 2008 | 2020 | ||||||||
|
ubiquilin 2 | 0.656 | 0.462 | 0.85 |
|
disease | 0.500 | None | 0.980 | 48 | 8 | 2011 | 2020 | ||||||||
|
angiogenin | 0.511 | 0.769 | 0.29 |
|
disease | 0.500 | None | 0.959 | 47 | 7 | 2004 | 2019 | ||||||||
|
profilin 1 | 0.565 | 0.769 | 0.73 |
|
disease | 0.500 | None | 1.000 | 35 | 5 | 2012 | 2019 | ||||||||
|
VAMP associated protein B and C | 0.666 | 0.423 | 0.58 |
|
disease | 0.500 | None | 0.967 | 29 | 3 | 2004 | 2019 | ||||||||
|
senataxin | 0.570 | 0.731 | 0.95 |
|
disease | 0.500 | moderate | 0.952 | 20 | 3 | 1998 | 2018 | ||||||||
|
neurofilament heavy | 0.588 | 0.769 | 2.7E-12 |
|
disease | 0.500 | None | 1.000 | 18 | 1 | 1993 | 2018 | ||||||||
|
heterogeneous nuclear ribonucleoprotein A1 | 0.529 | 0.885 | 1.00 |
|
disease | 0.500 | None | 1.000 | 17 | 2 | 2013 | 2019 | ||||||||
|
peripherin | 0.623 | 0.462 | 4.8E-14 |
|
disease | 0.500 | None | 1.000 | 17 | 1 | 2000 | 2016 |