| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.600 | None | 0.988 | 83 | 0 | 1999 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.400 | None | 0.947 | 75 | 1 | 1996 | 2019 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.400 | None | 0.898 | 49 | 1 | 1994 | 2018 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.400 | None | 0.974 | 39 | 2 | 2000 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 20 | 0 | 1996 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.400 | None | 0.950 | 20 | 4 | 2008 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.944 | 18 | 2 | 1995 | 2018 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.400 | None | 1.000 | 17 | 1 | 2010 | 2019 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
disease | 0.400 | None | 1.000 | 17 | 1 | 2013 | 2020 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
disease | 0.340 | None | 1.000 | 4 | 0 | 2002 | 2019 | ||||||||
|
speckle type BTB/POZ protein | 0.597 | 0.500 | 1.00 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2015 | 2018 | ||||||||
|
phosphoinositide-3-kinase regulatory subunit 2 | 0.551 | 0.808 | 1.6E-02 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2011 | 2011 | ||||||||
|
MYC associated factor X | 0.553 | 0.769 | 0.83 |
|
disease | 0.310 | None | 1.000 | 1 | 1 | 2018 | 2018 | ||||||||
|
PMS1 homolog 1, mismatch repair system component | 0.569 | 0.654 | 1.3E-17 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
ATR serine/threonine kinase | 0.456 | 0.923 | 3.5E-09 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.300 | None | 0.928 | 83 | 9 | 1994 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.280 | None | 0.889 | 8 | 0 | 2000 | 2019 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.250 | None | 1.000 | 5 | 0 | 2012 | 2015 | ||||||||
|
ERBB receptor feedback inhibitor 1 | 0.612 | 0.538 | 1.2E-02 |
|
disease | 0.230 | None | 1.000 | 3 | 0 | 2009 | 2017 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.100 | None | 0.963 | 107 | 6 | 1993 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 0.968 | 63 | 6 | 2004 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.100 | None | 0.962 | 53 | 7 | 2001 | 2019 | ||||||||
|
NDC80 kinetochore complex component | 0.599 | 0.538 | 1.1E-07 |
|
disease | 0.100 | None | 0.981 | 52 | 0 | 1991 | 2020 | ||||||||
|
progesterone receptor | 0.426 | 0.885 | 5.1E-02 |
|
disease | 0.100 | None | 0.962 | 52 | 4 | 1998 | 2020 | ||||||||
|
mannose receptor C-type 1 | 0.413 | 0.846 | 0.94 |
|
disease | 0.100 | None | 0.978 | 45 | 0 | 2003 | 2019 |