| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.400 | None | 0.981 | 35 | 0 | 1991 | 2020 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.400 | None | 0.986 | 13 | 0 | 1990 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.400 | None | 0.913 | 9 | 0 | 1993 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.400 | None | 0.990 | 7 | 0 | 1995 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.400 | None | 0.867 | 5 | 0 | 1997 | 2020 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 1997 | 2018 | ||||||||
|
acetylcholinesterase (Cartwright blood group) | 0.445 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.931 | 2 | 0 | 2002 | 2020 | ||||||||
|
triggering receptor expressed on myeloid cells 2 | 0.519 | 0.769 | 3.3E-09 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2003 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.909 | 1 | 0 | 1999 | 2018 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.875 | 1 | 0 | 1993 | 2020 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.400 | None | 0.951 | 1 | 0 | 1990 | 2019 | ||||||||
|
butyrylcholinesterase | 0.447 | 0.923 | 1.1E-13 |
|
disease | 0.400 | None | 0.973 | 1 | 0 | 1997 | 2020 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.400 | None | 0.909 | 1 | 0 | 2006 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2007 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.390 | None | 0.800 | 1 | 0 | 1993 | 2012 | ||||||||
|
clusterin | 0.426 | 0.885 | 7.8E-05 |
|
disease | 0.370 | None | 0.900 | 3 | 0 | 1998 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.370 | None | 0.875 | 1 | 0 | 1997 | 2016 | ||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
disease | 0.370 | None | 0.875 | 1 | 0 | 2005 | 2019 | ||||||||
|
cystatin C | 0.436 | 0.808 | 3.9E-03 |
|
disease | 0.350 | None | 1.000 | 2 | 0 | 1996 | 2019 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.350 | None | 0.833 | 1 | 0 | 2006 | 2017 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.350 | None | 1.000 | 1 | 0 | 2010 | 2018 | ||||||||
|
apolipoprotein C1 | 0.581 | 0.577 | 0.22 |
|
disease | 0.340 | None | 1.000 | 2 | 0 | 1998 | 2018 | ||||||||
|
cholinergic receptor nicotinic alpha 7 subunit | 0.532 | 0.654 | 4.2E-04 |
|
disease | 0.340 | None | 0.800 | 1 | 0 | 2007 | 2017 | ||||||||
|
translocase of outer mitochondrial membrane 40 | 0.590 | 0.538 | 0.99 |
|
disease | 0.330 | None | 1.000 | 4 | 0 | 2016 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.330 | None | 1.000 | 2 | 0 | 1999 | 2019 |