Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4487
Gene Symbol: MSX1
MSX1
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.700 GermlineCausalMutation ORPHANET

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.500 GermlineCausalMutation ORPHANET

Entrez Id: 5083
Gene Symbol: PAX9
PAX9
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.500 GermlineCausalMutation ORPHANET

Entrez Id: 1896
Gene Symbol: EDA
EDA
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.500 GermlineCausalMutation ORPHANET

Entrez Id: 80326
Gene Symbol: WNT10A
WNT10A
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.500 GermlineCausalMutation ORPHANET

Entrez Id: 4040
Gene Symbol: LRP6
LRP6
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.430 GermlineCausalMutation ORPHANET In three of the probands, we detected heterozygous variants in LRP6, and sequencing of additional oligodontia-affected individuals yielded one additional mutation in LRP6. 26387593

2015
Entrez Id: 7480
Gene Symbol: WNT10B
WNT10B
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.420 GermlineCausalMutation ORPHANET Mutations in WNT10B Are Identified in Individuals with Oligodontia. 27321946

2016
Entrez Id: 3664
Gene Symbol: IRF6
IRF6
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.420 GermlineCausalMutation ORPHANET

Entrez Id: 128178
Gene Symbol: EDARADD
EDARADD
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.420 GermlineCausalMutation ORPHANET

Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.410 GermlineCausalMutation ORPHANET

Entrez Id: 7341
Gene Symbol: SUMO1
SUMO1
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.400 GeneticVariation ORPHANET

Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0020608
Disease: Hypodontia
Hypodontia 		0.400 GermlineCausalMutation ORPHANET