Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 210
Gene Symbol: ALAD
ALAD
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.500 Biomarker CTD_human Investigation of delta-aminolevulinic acid dehydratase polymorphism affecting hematopoietic, hepatic and renal toxicity from lead in Han subjects of southwestern China. 24631795

2014
Entrez Id: 210
Gene Symbol: ALAD
ALAD
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.500 Biomarker CTD_human Lead concentration in plasma as a biomarker of exposure and risk, and modification of toxicity by δ-aminolevulinic acid dehydratase gene polymorphism. 23792432

2013
Entrez Id: 210
Gene Symbol: ALAD
ALAD
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.500 Biomarker CTD_human The difference in methylation frequencies between exposures and controls was statistically significant (p=0.002), and individuals with methylated ALAD gene showed an increased risk of lead poisoning (adjusted OR=3.57, 95% CI, 1.55-8.18). 21396434

2011
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.310 Biomarker CTD_human [Association of vitamin D receptor gene haplotypes and genotype combinations with susceptibility to occupational elevated blood lead]. 23433214

2013
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.310 Biomarker CTD_human Vitamin D receptor haplotypes affect lead levels during pregnancy. 20692022

2010
Entrez Id: 57510
Gene Symbol: XPO5
XPO5
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.300 Biomarker CTD_human Association between Polymorphism of Exportin-5 and Susceptibility to Lead Poisoning in a Chinese Population. 28042866

2016
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.300 Biomarker CTD_human The relationship between XRCC3 gene polymorphism and susceptibility to lead poisoning in male lead-exposed workers was analyzed. 23803535

2013
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.300 Biomarker CTD_human HFE gene variants modify the association between maternal lead burden and infant birthweight: a prospective birth cohort study in Mexico City, Mexico. 20659343

2010
Entrez Id: 84560
Gene Symbol: MT4
MT4
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.300 Biomarker CTD_human The association of metallothionein-4 gene polymorphism and renal function in long-term lead-exposed workers. 19921116

2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0023176
Disease: Lead Poisoning
Lead Poisoning 		0.300 Biomarker CTD_human Matrix metalloproteinase-9 activity in plasma correlates with plasma and whole blood lead concentrations. 16700817

2006