Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 114907
Gene Symbol: FBXO32
FBXO32
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.540 Biomarker RGD Identification of ubiquitin ligases required for skeletal muscle atrophy. 11679633

2001

Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.510 Biomarker RGD Identification of ubiquitin ligases required for skeletal muscle atrophy. 11679633

2001

Entrez Id: 1072
Gene Symbol: CFL1
CFL1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Decrease of Both Cofilin and LIM Kinase Phosphorylation in the Skeletal Muscles of Immobilization-induced Atrophy Rats. 24711688

2014

Entrez Id: 3297
Gene Symbol: HSF1
HSF1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Therapeutic RGD Biphasic stress response in the soleus during reloading after hind limb unloading. 21983076

2012

Entrez Id: 3326
Gene Symbol: HSP90AB1
HSP90AB1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Protective effect of L-Arginine administration on proteins of unloaded m. soleus. 21639837

2011

Entrez Id: 9804
Gene Symbol: TOMM20
TOMM20
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Effect of denervation-induced muscle disuse on mitochondrial protein import. 20943961

2011

Entrez Id: 100287932
Gene Symbol: TIMM23
TIMM23
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Effect of denervation-induced muscle disuse on mitochondrial protein import. 20943961

2011

Entrez Id: 1395
Gene Symbol: CRHR2
CRHR2
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Corticotrophin releasing factor 2 receptor (CRF2R) agonists have been shown to maintain skeletal muscle mass and force production in a variety of acute conditions that lead to skeletal muscle wasting. 21235761

2011

Entrez Id: 1147
Gene Symbol: CHUK
CHUK
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Therapeutic RGD The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy. 18827022

2009

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Plasminogen activator inhibitor type 1 up-regulation is associated with skeletal muscle atrophy and associated fibrosis. 19574431

2009

Entrez Id: 3551
Gene Symbol: IKBKB
IKBKB
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Therapeutic RGD The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy. 18827022

2009

Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 19125695

2009

Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Therapeutic RGD Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats. 19260063

2009

Entrez Id: 9110
Gene Symbol: MTMR4
MTMR4
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 19125695

2009

Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway. 17885021

2008

Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD TGF-beta1 and TNF-alpha are involved in the transcription of type I collagen alpha2 gene in soleus muscle atrophied by mechanical unloading. 17916675

2008

Entrez Id: 7037
Gene Symbol: TFRC
TFRC
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. 18395385

2008

Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Transcription factors in muscle atrophy caused by blocked neuromuscular transmission and muscle unloading in rats. 17622304

2007

Entrez Id: 1514
Gene Symbol: CTSL
CTSL
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Role for IkappaBalpha, but not c-Rel, in skeletal muscle atrophy. 16928772

2007

Entrez Id: 317
Gene Symbol: APAF1
APAF1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. 17029665

2006

Entrez Id: 2660
Gene Symbol: MSTN
MSTN
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD These results are consistent with the hypothesis that the increased serum levels of active form of myostatin protein, induced yet unknown post-translational control mechanisms may be responsible, at least in part, for the muscle wasting associated with the adrenal insufficiency syndromes. 15738643

2005

Entrez Id: 2021
Gene Symbol: ENDOG
ENDOG
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Age-related differences in apoptosis with disuse atrophy in soleus muscle. 15650125

2005

Entrez Id: 7050
Gene Symbol: TGIF1
TGIF1
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. 14718385

2004

Entrez Id: 2660
Gene Symbol: MSTN
MSTN
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD Myostatin expression in age and denervation-induced skeletal muscle atrophy. 15758361

2003

Entrez Id: 2690
Gene Symbol: GHR
GHR
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy
0.200 Biomarker RGD The present data suggest that muscle atrophy is associated with a muscle fiber type-specific GHR mRNA up-regulation mechanism that helps protect atrophying fibers in EDL but might be part of an attempt to repair in SOL. 12865352

2003