| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.900 | None | 1.000 | 0 | 0 | 1993 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.800 | None | 1.000 | 2 | 2 | 1996 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.974 | 6 | 0 | 1997 | 2019 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.700 | None | 1.000 | 0 | 0 | 1999 | 2016 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.650 | None | 0.857 | 2 | 0 | 2003 | 2017 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.620 | None | 1.000 | 1 | 0 | 2005 | 2015 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.610 | None | 1.000 | 1 | 1 | 2004 | 2015 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.440 | None | 1.000 | 2 | 0 | 2004 | 2015 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.440 | None | 1.000 | 1 | 0 | 2002 | 2018 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.430 | None | 1.000 | 0 | 0 | 2002 | 2017 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.420 | None | 1.000 | 1 | 0 | 2011 | 2015 | ||||||||
|
serine peptidase inhibitor Kazal type 1 | 0.492 | 0.808 | 0.31 |
|
disease | 0.410 | None | 1.000 | 1 | 0 | 2003 | 2009 | ||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
disease | 0.410 | None | 1.000 | 1 | 0 | 2005 | 2010 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
disease | 0.410 | None | 1.000 | 1 | 0 | 2014 | 2015 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2003 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2003 | 2019 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2003 | 2019 | ||||||||
|
WT1 transcription factor | 0.422 | 0.808 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
pancreatic and duodenal homeobox 1 | 0.530 | 0.654 | 1.8E-02 |
|
disease | 0.380 | None | 1.000 | 3 | 0 | 2003 | 2019 | ||||||||
|
menin 1 | 0.444 | 0.808 | 1.00 |
|
disease | 0.380 | None | 0.900 | 2 | 0 | 1991 | 2011 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.380 | None | 1.000 | 1 | 0 | 2003 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.370 | None | 1.000 | 1 | 0 | 2002 | 2018 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.370 | None | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.370 | None | 1.000 | 1 | 0 | 2000 | 2018 | ||||||||
|
CD44 molecule (Indian blood group) | 0.363 | 0.962 | 2.4E-07 |
|
disease | 0.360 | None | 1.000 | 1 | 0 | 2001 | 2019 |