| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 1987 | 2003 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 1989 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2007 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.900 | 10 | 0 | 2012 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 1990 | 2019 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2008 | 2018 | ||||||||
|
proteinase 3 | 0.503 | 0.808 | 3.8E-05 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2016 | 2019 | ||||||||
|
matrix metallopeptidase 3 | 0.408 | 0.885 | 5.7E-15 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2007 | 2019 | ||||||||
|
intercellular adhesion molecule 1 | 0.364 | 0.962 | 3.5E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1990 | 2019 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1992 | 2004 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.040 | None | 1.000 | 3 | 0 | 2000 | 2015 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1990 | 2019 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1995 | 2012 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2001 | 2006 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2011 | 2017 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1995 | 2017 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2002 | 2015 | ||||||||
|
secreted phosphoprotein 1 | 0.353 | 0.885 | 2.1E-06 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2005 | 2013 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1996 | 2012 | ||||||||
|
Cerebellar degeneration-related autoantigen-3 | 0.472 | 0.808 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2002 | 2009 | |||||||||
|
CD44 molecule (Indian blood group) | 0.363 | 0.962 | 2.4E-07 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2001 | 2013 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2010 | 2014 | ||||||||
|
prostaglandin-endoperoxide synthase 1 | 0.460 | 0.885 | 6.2E-07 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2009 | 2011 | ||||||||
|
nerve growth factor | 0.391 | 0.885 | 0.82 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2009 | 2019 | ||||||||
|
C-X9-C motif containing 1 | 0.711 | 0.308 | 0.11 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2018 | 2019 |