| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.600 | None | 0.867 | 76 | 5 | 1993 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.600 | None | 0.941 | 31 | 0 | 1993 | 2018 | ||||||||
|
natriuretic peptide A | 0.505 | 0.769 | 5.5E-04 |
|
disease | 0.560 | None | 1.000 | 4 | 1 | 1997 | 2014 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
disease | 0.550 | None | 1.000 | 5 | 0 | 1997 | 2016 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.520 | None | 1.000 | 2 | 0 | 2004 | 2018 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.400 | None | 1.000 | 32 | 2 | 1992 | 2019 | ||||||||
|
angiotensin II receptor type 2 | 0.496 | 0.808 | 8.2E-03 |
|
disease | 0.360 | None | 1.000 | 3 | 0 | 2002 | 2013 | ||||||||
|
growth differentiation factor 15 | 0.429 | 0.808 | 3.0E-07 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2009 | 2019 | ||||||||
|
myosin heavy chain 7 | 0.516 | 0.692 | 4.2E-16 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 1987 | 2016 | ||||||||
|
protein phosphatase 3 regulatory subunit B, alpha | 0.682 | 0.538 | 0.41 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2005 | 2008 | ||||||||
|
aryl hydrocarbon receptor | 0.410 | 0.923 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2003 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2009 | 2018 | ||||||||
|
chymase 1 | 0.514 | 0.692 | 7.6E-09 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2003 | 2005 | ||||||||
|
angiotensin I converting enzyme 2 | 0.477 | 0.769 | 1.00 |
|
disease | 0.280 | None | 1.000 | 7 | 2 | 2006 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.270 | None | 1.000 | 5 | 1 | 1997 | 2018 | ||||||||
|
adrenoceptor beta 1 | 0.555 | 0.769 | 2.9E-06 |
|
disease | 0.250 | None | 1.000 | 5 | 2 | 2002 | 2010 | ||||||||
|
natriuretic peptide B | 0.513 | 0.808 | 9.9E-06 |
|
disease | 0.250 | None | 1.000 | 2 | 0 | 2006 | 2018 | ||||||||
|
cellular communication network factor 2 | 0.399 | 0.846 | 5.0E-04 |
|
disease | 0.240 | None | 0.800 | 4 | 0 | 2009 | 2018 | ||||||||
|
cardiotrophin 1 | 0.636 | 0.423 | 4.2E-02 |
|
disease | 0.240 | None | 1.000 | 4 | 0 | 1996 | 2012 | ||||||||
|
G protein-coupled receptor kinase 2 | 0.532 | 0.654 | 1.00 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 1999 | 2015 | ||||||||
|
bradykinin receptor B2 | 0.585 | 0.808 | 0.12 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2002 | 2004 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2008 | 2019 | ||||||||
|
forkhead box O3 | 0.431 | 0.808 | 0.99 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2008 | 2019 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2009 | 2018 | ||||||||
|
protein tyrosine kinase 2 beta | 0.448 | 0.808 | 0.94 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2002 | 2007 |