Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.420 None 1.000 2 0 2014 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.400 None 1.000 10 0 2004 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.380 None 1.000 8 1 2009 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.340 None 1.000 4 2 2011 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.412 0.808 6.3E-02
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.320 None 1.000 2 0 1996 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
SRY-box transcription factor 2 0.405 0.808 0.71
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.320 None 0.667 2 0 2016 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.310 None 1.000 1 0 1996 2007
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.310 None 1.000 1 0 2012 2018
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.310 None 1.000 1 0 1984 2012
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.310 None 1.000 1 0 2009 2009
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.310 None 1.000 1 0 2011 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.240 None 1.000 4 0 2007 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.070 None 1.000 7 0 2011 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.060 None 1.000 6 0 2005 2019
Entrez Id: 83746
Gene Symbol: L3MBTL2
L3MBTL2
L3MBTL histone methyl-lysine binding protein 2 0.729 0.308 1.0E-08
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.040 None 1.000 4 0 1999 2019
Entrez Id: 26013
Gene Symbol: L3MBTL1
L3MBTL1
L3MBTL histone methyl-lysine binding protein 1 0.729 0.269 1.5E-12
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.040 None 1.000 4 0 1999 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.030 None 1.000 3 0 2010 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.030 None 1.000 3 0 2001 2018
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
prominin 1 0.410 0.846 1.9E-22
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.030 None 1.000 3 0 2006 2011
Entrez Id: 3098
Gene Symbol: HK1
HK1
hexokinase 1 0.542 0.731 0.91
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.020 None 1.000 2 0 2011 2017
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
atypical chemokine receptor 3 0.428 0.885 0.39
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.020 None 1.000 2 0 2015 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
isocitrate dehydrogenase (NADP(+)) 2 0.434 0.808 0.88
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain
disease 0.020 None 1.000 2 0 2010 2012