Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human The Modulatory Role of MicroRNA-873 in the Progression of KRAS-Driven Cancers. 30654191

2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells. 30703373

2019
Entrez Id: 693120
Gene Symbol: MIR33B
MIR33B
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 407026
Gene Symbol: MIR29C
MIR29C
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 79733
Gene Symbol: E2F8
E2F8
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Transcriptional E2F1/2/5/8 as potential targets and transcriptional E2F3/6/7 as new biomarkers for the prognosis of human lung carcinoma. 29754146

2018
Entrez Id: 7415
Gene Symbol: VCP
VCP
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Interleukin-6 induced overexpression of valosin-containing protein (VCP)/p97 is associated with androgen-independent prostate cancer (AIPC) progression. 29693262

2018
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Inhibition of estrogen receptor reduces connexin 43 expression in breast cancers. 29180066

2018
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 407055
Gene Symbol: MIR99A
MIR99A
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 1874
Gene Symbol: E2F4
E2F4
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Transcriptional E2F1/2/5/8 as potential targets and transcriptional E2F3/6/7 as new biomarkers for the prognosis of human lung carcinoma. 29754146

2018
Entrez Id: 144455
Gene Symbol: E2F7
E2F7
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Transcriptional E2F1/2/5/8 as potential targets and transcriptional E2F3/6/7 as new biomarkers for the prognosis of human lung carcinoma. 29754146

2018
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride. 30132517

2018
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progression. 29179997

2018
Entrez Id: 1294
Gene Symbol: COL7A1
COL7A1
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462

2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462

2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Cyclin D1 promoter -56 and -54bp CpG un-methylation predicts invasive progression in arsenic-induced Bowen's disease. 29103775

2018
Entrez Id: 406892
Gene Symbol: MIR100
MIR100
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462

2018
Entrez Id: 100422979
Gene Symbol: MIR4324
MIR4324
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride. 30132517

2018
Entrez Id: 1870
Gene Symbol: E2F2
E2F2
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Transcriptional E2F1/2/5/8 as potential targets and transcriptional E2F3/6/7 as new biomarkers for the prognosis of human lung carcinoma. 29754146

2018
Entrez Id: 407041
Gene Symbol: MIR34B
MIR34B
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human A Panel of MicroRNA Signature as a Tool for Predicting Survival of Patients with Urothelial Carcinoma of the Bladder. 30026881

2018
Entrez Id: 1875
Gene Symbol: E2F5
E2F5
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Transcriptional E2F1/2/5/8 as potential targets and transcriptional E2F3/6/7 as new biomarkers for the prognosis of human lung carcinoma. 29754146

2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462

2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0235874
Disease: Disease Exacerbation
Disease Exacerbation 		0.300 Biomarker CTD_human Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. 29106415

2017