Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 0.962 52 1 1995 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
alpha fetoprotein 0.429 0.885 1.1E-11
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 0.971 34 0 1997 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 22 0 1998 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 18 1 2003 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 0.812 16 2 2005 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 16 0 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 13 1 2002 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 13 0 2017 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 11 0 2017 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 0.900 10 0 1996 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 1.000 10 0 2002 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.100 None 0.900 10 0 1992 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.090 None 1.000 9 0 2006 2019
Entrez Id: 354
Gene Symbol: KLK3
KLK3
kallikrein related peptidase 3 0.443 0.885 4.4E-06
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.090 None 0.556 9 0 1995 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.080 None 0.875 8 0 2001 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.080 None 1.000 8 0 2006 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.070 None 1.000 7 0 2011 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.070 None 0.857 7 0 2005 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.070 None 1.000 7 0 2009 2011
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.060 None 0.833 6 0 2011 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.060 None 0.833 6 0 2000 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.060 None 1.000 6 0 2008 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.060 None 1.000 6 0 2006 2019
Entrez Id: 346389
Gene Symbol: MACC1
MACC1
MET transcriptional regulator MACC1 0.561 0.538 6.0E-19
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.050 None 1.000 5 0 2011 2016
Entrez Id: 5460
Gene Symbol: POU5F1
POU5F1
POU class 5 homeobox 1 0.441 0.846 0.95
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
phenotype 0.050 None 1.000 5 0 2014 2018