Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 0.979 481 5 2002 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		epidermal growth factor receptor 0.295 0.885 0.37
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 36 1 2010 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 32 3 2005 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		estrogen receptor 1 0.324 0.962 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 27 0 2010 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 20 0 2005 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 20 0 2005 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 20 0 2005 2020
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		cyclin dependent kinase 4 0.412 0.808 6.3E-02
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 14 0 2013 2020
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		erb-b2 receptor tyrosine kinase 3 0.448 0.808 1.7E-15
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 13 0 2010 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		CD274 molecule 0.324 0.923 1.9E-02
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.100 None 1.000 10 0 2017 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.090 None 1.000 9 0 2013 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.090 None 1.000 9 1 2010 2019
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1 		heat shock protein 90 alpha family class A member 1 0.411 0.923 0.86
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.070 None 1.000 7 0 2013 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.060 None 0.833 6 1 2010 2017
Entrez Id: 2194
Gene Symbol: FASN
FASN 		fatty acid synthase 0.474 0.846 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.050 None 1.000 5 0 2011 2018
Entrez Id: 367
Gene Symbol: AR
AR 		androgen receptor 0.351 0.846 0.99
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.050 None 1.000 5 0 2016 2018
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		cytochrome P450 family 19 subfamily A member 1 0.410 0.885 1.7E-05
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 0 2018 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		epidermal growth factor 0.357 0.923 8.5E-17
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 0 2015 2019
Entrez Id: 1869
Gene Symbol: E2F1
E2F1 		E2F transcription factor 1 0.441 0.846 0.99
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 0 2013 2018
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		erb-b2 receptor tyrosine kinase 4 0.455 0.846 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 1 2013 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 0 2015 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.040 None 1.000 4 0 2017 2018
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B 		protein tyrosine kinase 2 beta 0.448 0.808 0.94
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.030 None 1.000 3 0 2010 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		BRCA1 DNA repair associated 0.367 0.923 9.2E-29
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.030 None 1.000 3 0 2016 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		interleukin 6 0.248 0.962 0.32
CUI: C1960398
Disease: HER2-positive carcinoma of breast
HER2-positive carcinoma of breast 		disease 0.030 None 1.000 3 0 2012 2017