| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
bone morphogenetic protein receptor type 2 | 0.538 | 0.654 | 1.00 |
|
disease | 0.500 | None | 0.927 | 54 | 2 | 2002 | 2020 | ||||||||
|
activin A receptor like type 1 | 0.493 | 0.769 | 9.7E-04 |
|
disease | 0.500 | strong | 0.909 | 11 | 0 | 2002 | 2019 | ||||||||
|
caveolin 1 | 0.388 | 0.885 | 8.3E-03 |
|
disease | 0.500 | moderate | 0.909 | 10 | 0 | 2012 | 2019 | ||||||||
|
potassium two pore domain channel subfamily K member 3 | 0.584 | 0.654 | 0.90 |
|
disease | 0.460 | strong | 0.857 | 6 | 0 | 2016 | 2019 | ||||||||
|
eukaryotic translation initiation factor 2 alpha kinase 4 | 0.603 | 0.577 | 1.2E-15 |
|
disease | 0.440 | strong | 1.000 | 4 | 0 | 2015 | 2019 | ||||||||
|
T-box transcription factor 4 | 0.576 | 0.731 | 0.50 |
|
disease | 0.420 | strong | 1.000 | 2 | 0 | 2013 | 2016 | ||||||||
|
SMAD family member 9 | 0.666 | 0.308 | 6.4E-05 |
|
disease | 0.420 | None | 0.667 | 2 | 0 | 2013 | 2015 | ||||||||
|
endothelial PAS domain protein 1 | 0.454 | 0.731 | 0.60 |
|
disease | 0.320 | strong | 1.000 | 2 | 0 | 2008 | 2018 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.150 | None | 1.000 | 5 | 0 | 2010 | 2020 | ||||||||
|
growth differentiation factor 2 | 0.529 | 0.731 | 2.5E-03 |
|
disease | 0.140 | None | 1.000 | 4 | 0 | 2015 | 2020 | ||||||||
|
notch receptor 1 | 0.369 | 0.885 | 1.00 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2015 | 2019 | ||||||||
|
endoglin | 0.446 | 0.846 | 1.00 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2007 | 2016 | ||||||||
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.110 | None | < 0.001 | 1 | 0 | 2009 | 2009 | ||||||||
|
Janus kinase 2 | 0.385 | 0.885 | 0.65 |
|
disease | 0.110 | None | < 0.001 | 1 | 0 | 2016 | 2016 | ||||||||
|
carbohydrate sulfotransferase 3 | 0.517 | 0.846 | 7.2E-03 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
cellular communication network factor 2 | 0.399 | 0.846 | 5.0E-04 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 2010 | 2019 | ||||||||
|
phenylalanine hydroxylase | 0.516 | 0.769 | 6.4E-23 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2012 | 2019 | ||||||||
|
phosphodiesterase 5A | 0.513 | 0.731 | 1.1E-04 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2007 | 2020 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2008 | 2019 | ||||||||
|
secretory leukocyte peptidase inhibitor | 0.449 | 0.846 | 9.0E-04 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 2003 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2007 | 2020 | ||||||||
|
galectin 3 | 0.392 | 0.846 | 2.3E-05 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2017 | 2019 | ||||||||
|
apelin receptor | 0.588 | 0.692 | 0.79 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2019 |