Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
bone morphogenetic protein receptor type 2 0.538 0.654 1.00
Idiopathic pulmonary arterial hypertension
disease 0.700 None 0.978 184 4 2000 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
Idiopathic pulmonary arterial hypertension
disease 0.700 moderate 0.955 21 0 2007 2019
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3
potassium two pore domain channel subfamily K member 3 0.584 0.654 0.90
Idiopathic pulmonary arterial hypertension
disease 0.700 strong 0.952 20 0 2012 2020
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
SMAD family member 9 0.666 0.308 6.4E-05
Idiopathic pulmonary arterial hypertension
disease 0.660 None 0.857 6 0 2009 2018
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
Idiopathic pulmonary arterial hypertension
disease 0.500 strong 0.971 34 1 2001 2020
Entrez Id: 9496
Gene Symbol: TBX4
TBX4
T-box transcription factor 4 0.576 0.731 0.50
Idiopathic pulmonary arterial hypertension
disease 0.460 strong 1.000 6 0 2013 2020
Entrez Id: 440275
Gene Symbol: EIF2AK4
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4 0.603 0.577 1.2E-15
Idiopathic pulmonary arterial hypertension
disease 0.440 strong 1.000 4 0 2015 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
Idiopathic pulmonary arterial hypertension
disease 0.420 None 1.000 2 0 2008 2018
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.606 0.500 1.1E-03
Idiopathic pulmonary arterial hypertension
disease 0.360 None 0.857 6 1 2007 2019
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
SMAD family member 1 0.533 0.731 0.99
Idiopathic pulmonary arterial hypertension
disease 0.350 None 1.000 5 0 2010 2019
Entrez Id: 658
Gene Symbol: BMPR1B
BMPR1B
bone morphogenetic protein receptor type 1B 0.573 0.615 1.00
Idiopathic pulmonary arterial hypertension
disease 0.320 limited 1.000 2 0 2004 2012
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
endothelial PAS domain protein 1 0.454 0.731 0.60
Idiopathic pulmonary arterial hypertension
disease 0.320 strong 1.000 2 0 2008 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
Idiopathic pulmonary arterial hypertension
disease 0.200 None 1.000 17 0 2008 2020
Entrez Id: 2022
Gene Symbol: ENG
ENG
endoglin 0.446 0.846 1.00
Idiopathic pulmonary arterial hypertension
disease 0.200 None 1.000 14 1 2006 2019
Entrez Id: 2658
Gene Symbol: GDF2
GDF2
growth differentiation factor 2 0.529 0.731 2.5E-03
Idiopathic pulmonary arterial hypertension
disease 0.190 None 1.000 9 0 2015 2020
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
Idiopathic pulmonary arterial hypertension
disease 0.130 None 1.000 3 0 2017 2019
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
filamin A 0.419 0.846 1.00
Idiopathic pulmonary arterial hypertension
disease 0.120 None 1.000 2 0 2019 2019
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
Janus kinase 2 0.385 0.885 0.65
Idiopathic pulmonary arterial hypertension
disease 0.120 None 1.000 2 1 2011 2016
Entrez Id: 8517
Gene Symbol: IKBKG
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 0.493 0.769 8.5E-02
Idiopathic pulmonary arterial hypertension
disease 0.120 None 1.000 2 0 2017 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
notch receptor 1 0.369 0.885 1.00
Idiopathic pulmonary arterial hypertension
disease 0.120 None 1.000 2 0 2015 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
Idiopathic pulmonary arterial hypertension
disease 0.120 None 0.500 2 0 1996 2009
Entrez Id: 9469
Gene Symbol: CHST3
CHST3
carbohydrate sulfotransferase 3 0.517 0.846 7.2E-03
Idiopathic pulmonary arterial hypertension
disease 0.110 None 1.000 1 0 2018 2018
Entrez Id: 6440
Gene Symbol: SFTPC
SFTPC
surfactant protein C 0.556 0.692 7.5E-04
Idiopathic pulmonary arterial hypertension
disease 0.110 None 1.000 1 0 2011 2011
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
fibroblast growth factor receptor 1 0.362 0.885 1.00
Idiopathic pulmonary arterial hypertension
disease 0.110 None 1.000 1 0 2013 2013
Entrez Id: 27247
Gene Symbol: NFU1
NFU1
NFU1 iron-sulfur cluster scaffold 0.769 0.231 4.1E-06
Idiopathic pulmonary arterial hypertension
disease 0.110 None 1.000 1 1 2020 2020