Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.100 GeneticVariation LHGDN Use of several collections of OA samples allowed us to obtain sound evidence against the participation of genetic variation in ADAMTS-5 in OA susceptibility. 18240210

2008
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.100 Biomarker LHGDN Expression of ADAMTS-5 in deformed human temporomandibular joint discs. 18830934

2008
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.100 Biomarker LHGDN Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5. 17265492

2007
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.100 AlteredExpression LHGDN Furthermore, OA, RA, and nonarthritis ST contained similar amounts of immunoreactive aggrecanase-2. 11801682

2002
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.030 AlteredExpression LHGDN Expression and regulation of aggrecanase in arthritis: the role of TGF-beta. 11801682

2002
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 AlteredExpression LHGDN These results demonstrate for the first time that ADAMTS-5 is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 may play a role in glioma cell invasion through the cleavage of brevican. 16133547

2005
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0017638
Disease: Glioma
Glioma 		0.010 AlteredExpression LHGDN These results demonstrate for the first time that ADAMTS-5 is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 may play a role in glioma cell invasion through the cleavage of brevican. 16133547

2005
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.010 Biomarker LHGDN The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican. 15599946

2005