Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.500 Biomarker RGD Enhancement of methoxamine-induced contractile responses of rat ventricular muscle in streptozotocin-induced diabetes is associated with alpha1A adrenoceptor upregulation. 17054657

2007

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.300 Biomarker RGD Captopril therapy decreases both expression and function of alpha-adrenoceptors in pre- hypertensive rat aorta. 16371063

2006

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0005694
Disease: Bladder neck obstruction
Bladder neck obstruction
0.210 Biomarker RGD Alpha1-adrenoceptor antagonists improve bladder storage function through reduction of afferent activity in rats with bladder outlet obstruction. 20886573

2011

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0025261
Disease: Memory Disorders
Memory Disorders
0.200 Biomarker RGD Altered adrenergic receptor signaling following traumatic brain injury contributes to working memory dysfunction. 20974230

2011

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0042024
Disease: Urinary Incontinence
Urinary Incontinence
0.200 Biomarker RGD A selective alpha1A-adrenoceptor antagonist inhibits detrusor overactivity in a rat model of benign prostatic hyperplasia. 16890732

2006

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.200 Biomarker RGD Ovarian expression of alpha (1)- and beta (2)-adrenoceptors and p75 neurotrophin receptors in rats with steroid-induced polycystic ovaries. 15795180

2005

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0020649
Disease: Hypotension
Hypotension
0.200 Biomarker RGD Evidence that NAN-190-induced hypotension involves vascular alpha1-adrenoceptor antagonism in the rat. 12433595

2002

Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.200 Biomarker RGD Alpha1-adrenoceptors involvement in painful diabetic neuropathy: a role in allodynia. 10841349

2000