Source: CTD_mouse

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.600 Biomarker CTD_mouse [The expression of AT1A receptor and its modulation by benazepril in the renal tubulointerstitial lesions induced by ureteral obstruction]. 9596920

1997

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
0.230 Biomarker CTD_mouse Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice. 17350036

2007

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C1623038
Disease: Cirrhosis
Cirrhosis
0.230 Biomarker CTD_mouse [The expression of AT1A receptor and its modulation by benazepril in the renal tubulointerstitial lesions induced by ureteral obstruction]. 9596920

1997

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.210 Biomarker CTD_mouse Early fructose dietary treatment results in moderate hypertension and glucose intolerance, which is prevented by a single neonatal treatment with AT1R-AS. 11564974

2001

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0016059
Disease: Fibrosis
Fibrosis
0.210 Biomarker CTD_mouse [The expression of AT1A receptor and its modulation by benazepril in the renal tubulointerstitial lesions induced by ureteral obstruction]. 9596920

1997

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.200 Biomarker CTD_mouse Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.200 Biomarker CTD_mouse These data suggest that the AT1 receptor plays a crucial role in the development of cardiac hypertrophy and oxidative stress under excessive beta-adrenergic stimulation, and that ARB treatment is beneficial for sympatho-excitatory cardiac hypertrophy and failure in mice. 17350036

2007

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0019284
Disease: Diaphragmatic Hernia
Diaphragmatic Hernia
0.200 Biomarker CTD_mouse Altered renin-angiotensin system gene expression causes renal hypoplasia in the rats with nitrofen-induced diaphragmatic hernia. 16292651

2006

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental
0.200 Biomarker CTD_mouse AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4). 12890498

2003

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental
0.200 Biomarker CTD_mouse Enhanced expression of angiotensin II receptor subtypes and angiotensin converting enzyme in medroxyprogesterone-induced mouse mammary adenocarcinomas. 8389152

1993

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0206692
Disease: Carcinoma, Lobular
Carcinoma, Lobular
0.200 Biomarker CTD_mouse Enhanced expression of angiotensin II receptor subtypes and angiotensin converting enzyme in medroxyprogesterone-induced mouse mammary adenocarcinomas. 8389152

1993

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C1176475
Disease: Ductal Carcinoma
Ductal Carcinoma
0.200 Biomarker CTD_mouse Enhanced expression of angiotensin II receptor subtypes and angiotensin converting enzyme in medroxyprogesterone-induced mouse mammary adenocarcinomas. 8389152

1993