Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C1847823
Disease: CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2F
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2F 		0.760 Biomarker CTD_human

Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C2608087
Disease: NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IIB
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IIB 		0.700 Biomarker CTD_human

Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 Biomarker CTD_human These identified proteins, which include stratifin (14-3-3), transgelin 2, heat-shock protein (HSP)70, HSP27, manganese superoxide dismutase, prohibitin, DJ1, α-enolase, peroxiredoxin 6, aldo-keto reductase family member B10, phosphoglycerate kinase 1, α-1-antitrypsin and nm23-H1, may play a role in the development of HCC. 21472284

2012
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.360 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.350 Biomarker CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141

2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.340 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.330 Biomarker CTD_human Interestingly, while Hsp32 and Hsp70 expression was transient, Hsp25 demonstrated a sustained induction pattern, which may reflect an additional role of Hsp25 in subsequent remodeling events in the days following SE. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.330 Biomarker CTD_human Comparative proteome analysis of human adenocarcinoma. 19381893

2010
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.330 Biomarker CTD_human Discovery of epigenetically silenced genes in acute myeloid leukemias. 17330099

2007
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.330 Biomarker CTD_human These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells. 12855565

2003
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.320 Biomarker CTD_human Differential protein profiling in renal-cell carcinoma. 15108329

2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
Conventional (Clear Cell) Renal Cell Carcinoma 		0.320 Biomarker CTD_human Differential protein profiling in renal-cell carcinoma. 15108329

2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.310 Therapeutic CTD_human Transgenic mice (TG) with cardiac specific over-expression of Hsp27 and their wild type littermates (WT) were challenged with doxorubicin (25 mg/kg, IP) to induce HF. 17481944

2007
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.310 Biomarker CTD_human Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. 12878215

2003
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0011616
Disease: Contact Dermatitis
Contact Dermatitis 		0.300 Biomarker CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174

2015
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0162351
Disease: Contact hypersensitivity
Contact hypersensitivity 		0.300 Biomarker CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174

2015
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0270823
Disease: Petit mal status
Petit mal status 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0311335
Disease: Grand Mal Status Epilepticus
Grand Mal Status Epilepticus 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0751522
Disease: Status Epilepticus, Subclinical
Status Epilepticus, Subclinical 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0751523
Disease: Non-Convulsive Status Epilepticus
Non-Convulsive Status Epilepticus 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0751524
Disease: Simple Partial Status Epilepticus
Simple Partial Status Epilepticus 		0.300 Biomarker CTD_human Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. 20971094

2011
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0020507
Disease: Hyperplasia
Hyperplasia 		0.300 Biomarker CTD_human Our results suggest that HSP27 may play a role in the development of processes leading to intimal hyperplasia in HSV, and reduction of HSP27 phosphorylation by MK2i may be a potential strategy to inhibit the development of intimal hyperplasia in HSV to prevent the autologous vascular graft failure. 20864298

2010
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0040411
Disease: Tongue Neoplasms
Tongue Neoplasms 		0.300 Biomarker CTD_human Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis. 19840781

2010