Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0018824
Disease: Heart valve disease
Heart valve disease 		0.500 Therapeutic RGD Therefore, we sought to determine whether cyproheptadine, a 5-HT(2B)R antagonist, might prevent toxic valvulopathy in an animal model of pergolide-induced valvular heart disease. 19346455

2009
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0018801
Disease: Heart failure
Heart failure 		0.500 Biomarker RGD Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. 17936780

2007
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.500 Biomarker RGD Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. 17936780

2007
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0079485
Disease: Heart Valve Prolapse
Heart Valve Prolapse 		0.200 Therapeutic RGD Cyproheptadine prevents pergolide-induced valvulopathy in rats: an echocardiographic and histopathological study. 19346455

2009
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.200 Biomarker RGD A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. 16936262

2006
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0007194
Disease: Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy 		0.200 Biomarker MGD

Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
CUI: C0949658
Disease: Cardiomyopathy, Hypertrophic, Familial
Cardiomyopathy, Hypertrophic, Familial 		0.200 Biomarker MGD