Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0243026
Disease: Sepsis
Sepsis 		0.600 Biomarker RGD Effects of melatonin on cytokine release and healing of colonic anastomoses in an experimental sepsis model. 27598601

2016
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.600 Biomarker RGD The role of endogenous interferon-gamma (IFN gamma) in the development of insulin-dependent diabetes mellitus (IDDM) in diabetes-prone BB rats was evaluated. 8977415

1997
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker RGD IL-2 and IFN-gamma in the retina of diabetic rats. 20213480

2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0028754
Disease: Obesity
Obesity 		0.300 Biomarker RGD [Effects of leptin on airway inflammation and the expression of Th1/Th2 cytokines in asthmatic rats]. 19575934

2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0026918
Disease: Mycobacterium Infections
Mycobacterium Infections 		0.300 Biomarker RGD Higher susceptibility of type 1 diabetic rats to Mycobacterium tuberculosis infection. 19060451

2008
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0017638
Disease: Glioma
Glioma 		0.300 Biomarker RGD Transfectant glioma cell clones expressing either rat interferon-gamma (IFN-gamma), rat interleukin-7 (IL-7), or rat B7-1 were selected. 10078962

1999
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0376618
Disease: Endotoxemia
Endotoxemia 		0.250 Biomarker RGD Correlations between endotoxin, interferon-gamma, biopterin and serum phospholipase A2-activities during lethal gram negative sepsis in rats. 9195172

1997
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0920350
Disease: Autoimmune thyroiditis
Autoimmune thyroiditis 		0.240 Biomarker RGD To characterize the lymphocytic thyroiditis (LT) of BB/W rats further and to evaluate early increases of cytokine gene expression in LT, we investigated the interleukin (IL)-2, -4, -6, -10, -12p40, interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) gene expression in the thyroids, spleens, and livers of BB/W rats with and without histological evidence for thyroiditis. 10560963

1999
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.230 ModifyingMutation RGD Expression of tumor necrosis factor-alpha, interleukin-6, and interferon-gamma in spontaneous chronic pancreatitis in the WBN/Kob rat. 11345142

2001
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis 		0.220 Therapeutic RGD Interferon-gamma inhibits experimental renal fibrosis. 10594787

1999
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0349566
Disease: Squamous cell carcinoma of tongue
Squamous cell carcinoma of tongue 		0.210 ModifyingMutation RGD Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO. 17338814

2007
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.210 Biomarker RGD Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells. 10078962

1999
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0013395
Disease: Dyspepsia
Dyspepsia 		0.200 Therapeutic RGD Sini-san improves duodenal tight junction integrity in a rat model of functional dyspepsia. 28854971

2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury 		0.200 Biomarker RGD In vivo effect of surfactant on inflammatory cytokines during endotoxin-induced lung injury in rodents. 21767135

2012
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0029866
Disease: Other ureteric obstruction
Other ureteric obstruction 		0.200 Biomarker RGD Interferon-γ improves renal interstitial fibrosis and decreases intrarenal vascular resistance of hydronephrosis in an animal model. 21216449

2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.200 Biomarker RGD Effect of intravenous immunoglobulin treatment on brain interferon-gamma and interleukin-6 levels in a rat kindling model. 19944569

2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker RGD Protective effect of new nitrosothiols on the early inflammatory response to kidney ischemia/reperfusion and transplantation in rats. 19514843

2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0036982
Disease: Shock, Hemorrhagic
Shock, Hemorrhagic 		0.200 Biomarker RGD [The influences of propofol on corticosteroid and immunity of rats after hemorrhagic shock and resuscitation]. 19439114

2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0002103
Disease: Atopic rhinitis
Atopic rhinitis 		0.200 Therapeutic RGD [Treatment of allergic rhinitis rats by intranasal interferon gamma]. 18510219

2008
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0014236
Disease: Endophthalmitis
Endophthalmitis 		0.200 Biomarker RGD Expression of TNF-alpha, IL-1beta, and IFN-gamma in Staphylococcus epidermidis slime-positive experimental endophthalmitis is closely related to clinical inflammatory scores. 16544114

2006
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0009766
Disease: Allergic Conjunctivitis
Allergic Conjunctivitis 		0.200 Biomarker RGD Interferon gamma (IFN-gamma) knockout mice exhibit severe allergic conjunctivitis (AC), indicating that IFN-gamma regulates the development of AC. 12234900

2002
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0034103
Disease: Pulpitis
Pulpitis 		0.200 Biomarker RGD T lymphocyte subpopulations and interleukin-2, interferon-gamma, and interleukin-4 in rat pulpitis experimentally induced by specific bacteria. 12017181

2002
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0007932
Disease: Chagas' disease without mention of organ involvement
Chagas' disease without mention of organ involvement 		0.200 Biomarker RGD Protected Trypanosoma cruzi infection in rats born to mothers receiving interferon-gamma during gestation is associated with a decreased intramacrophage parasite growth and preferential synthesis of specific IgG2b antibodies. 10684988

2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0030343
Disease: Panuveitis
Panuveitis 		0.200 Biomarker RGD Interferon gamma immunoreactivity in iris nerve fibres during endotoxin induced uveitis in the rat. 9797675

1998
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0085129
Disease: Bronchial Hyperreactivity
Bronchial Hyperreactivity 		0.200 Biomarker RGD Expression of Th-2 cytokines interleukin-4 and -5 and of Th-1 cytokine interferon-gamma in ovalbumin-exposed sensitized Brown-Norway rats. 8690457

1996