Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.510 Biomarker RGD Exogenous interleukin-6 facilitated the contraction of the colon in a depression rat model. 23589140

2013
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.320 Biomarker RGD Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. 12123772

2002
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0018801
Disease: Heart failure
Heart failure 		0.210 Biomarker RGD Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure. 17095650

2007
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.210 Biomarker RGD Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure. 17095650

2007
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0015967
Disease: Fever
Fever 		0.200 Biomarker CTD_mouse Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis. 25429137

2014
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.200 Biomarker RGD Dynamic response to peripheral nerve injury detected by in situ hybridization of IL-6 and its receptor mRNAs in the dorsal root ganglia is not strictly correlated with signs of neuropathic pain. 23953943

2013
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0238281
Disease: Middle Cerebral Artery Syndrome
Middle Cerebral Artery Syndrome 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0740376
Disease: Middle Cerebral Artery Thrombosis
Middle Cerebral Artery Thrombosis 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0740391
Disease: Middle Cerebral Artery Occlusion
Middle Cerebral Artery Occlusion 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0751845
Disease: Middle Cerebral Artery Embolus
Middle Cerebral Artery Embolus 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0751846
Disease: Left Middle Cerebral Artery Infarction
Left Middle Cerebral Artery Infarction 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0751847
Disease: Embolic Infarction, Middle Cerebral Artery
Embolic Infarction, Middle Cerebral Artery 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0751848
Disease: Thrombotic Infarction, Middle Cerebral Artery
Thrombotic Infarction, Middle Cerebral Artery 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0751849
Disease: Right Middle Cerebral Artery Infarction
Right Middle Cerebral Artery Infarction 		0.200 Biomarker CTD_mouse Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. 21940958

2011
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy 		0.200 Biomarker RGD Satellite glial cells express IL-6 and corresponding signal-transducing receptors in the dorsal root ganglia of rat neuropathic pain model. 20519054

2010
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0029191
Disease: Orchitis
Orchitis 		0.200 Biomarker RGD Interleukin-6 and IL-6 receptor cell expression in testis of rats with autoimmune orchitis. 16458979

2006
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.200 Biomarker RGD Expression of cytokines and cytokine receptors in the rat brain after kainic acid-induced seizures. 12591161

2003
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
CUI: C0001349
Disease: Acute-Phase Reaction
Acute-Phase Reaction 		0.200 Biomarker RGD The cDNA clones were used to demonstrate that rat liver IL6-R mRNA concentrations were increased 4.2-fold at 12 h after the induction of an experimental acute-phase response. 2174054

1990