Source: INFERRED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		1.000 CausalMutation CLINVAR Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. 21592955

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		1.000 CausalMutation CLINVAR Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. 20938745

2010
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		1.000 CausalMutation CLINVAR Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis. 20133622

2010
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		1.000 GeneticVariation CLINVAR

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0342276
Disease: Maturity onset diabetes mellitus in young
Maturity onset diabetes mellitus in young 		0.900 Biomarker HPO

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASCAT Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study. 31152121

2019
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 GeneticVariation GWASCAT First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. 30254083

2018
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASCAT Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. 25751624

2015
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 GeneticVariation CLINVAR INS-gene mutations: from genetics and beta cell biology to clinical disease. 25542748

2015
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 GeneticVariation CLINVAR INS-gene mutations: from genetics and beta cell biology to clinical disease. 25542748

2015
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 GeneticVariation CLINVAR Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY). 20226046

2010
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 GeneticVariation CLINVAR Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY). 20226046

2010
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 GeneticVariation CLINVAR Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. 18192540

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 GeneticVariation CLINVAR Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. 18162506

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 GeneticVariation CLINVAR Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. 18192540

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 GeneticVariation CLINVAR Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. 18162506

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 GeneticVariation CLINVAR Insulin gene mutations as a cause of permanent neonatal diabetes. 17855560

2007
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 GeneticVariation CLINVAR Insulin gene mutations as a cause of permanent neonatal diabetes. 17855560

2007
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Biomarker HPO

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.700 Biomarker HPO

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.700 Biomarker HPO

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0342283
Disease: Hyperproinsulinemia
Hyperproinsulinemia 		0.700 CausalMutation CLINVAR

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1852092
Disease: DIABETES MELLITUS, INSULIN-DEPENDENT, 2
DIABETES MELLITUS, INSULIN-DEPENDENT, 2 		0.700 CausalMutation CLINVAR

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C3150617
Disease: Maturity-onset diabetes of the young, type 10
Maturity-onset diabetes of the young, type 10 		0.700 CausalMutation CLINVAR