Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker RGD Streptozotocin-induced diabetes increases the interaction of Bad/Bcl-XL and decreases the binding of pBad/14-3-3 in rat testis. 17870134

2007
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.500 Biomarker RGD Transduction of anti-cell death protein FNK protects isolated rat hearts from myocardial infarction induced by ischemia/reperfusion. 17467744

2007
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction 		0.500 Biomarker RGD We hypothesized that apoptosis is a downstream event in erectile dysfunction, and pro-apoptotic (Bak and Bax) and anti-apoptotic (Bcl-2 and Bcl-x) factors are involved in the etiology of aging erectile dysfunction. 12394778

2002
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		0.210 Therapeutic RGD We have constructed a powerful antiapoptotic modified Bcl-X(L) protein (originally constructed from Bcl-X(L)) fused with PTD derived from TAT (TAT-modified Bcl-X(L)), and, to examine its clinical effectiveness in a mouse model of familial amyotrophic lateral sclerosis (ALS), transgenic mice expressing human Cu/Zn superoxide dismutase (SOD1) bearing a G93A mutation were treated by intrathecal infusion of TAT-modified Bcl-X(L). 18543336

2008
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.200 Biomarker RGD Involvement of caspases and their upstream regulators in myocardial apoptosis in a rat model of selenium deficiency-induced dilated cardiomyopathy. 26004897

2015
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.200 Therapeutic RGD A novel angiogenesis inhibitor bevacizumab induces apoptosis in the rat endometriosis model. 25937801

2014
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0038220
Disease: Status Epilepticus
Status Epilepticus 		0.200 Biomarker RGD The effect of STAT3 inhibition on status epilepticus and subsequent spontaneous seizures in the pilocarpine model of acquired epilepsy. 24051278

2014
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental 		0.200 Therapeutic RGD Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. 23404339

2013
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0038358
Disease: Gastric ulcer
Gastric ulcer 		0.200 Therapeutic RGD Cytoprotective effect of American ginseng in a rat ethanol gastric ulcer model. 24378970

2013
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0752308
Disease: Hypoxia-Ischemia, Brain
Hypoxia-Ischemia, Brain 		0.200 Biomarker RGD Identification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia-ischemia. 24195677

2013
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Therapeutic RGD Erythropoietin, but not asialoerythropoietin or carbamyl-erythropoietin, attenuates monocrotaline-induced pulmonary hypertension in rats. 22559233

2012
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.200 Therapeutic RGD Venlafaxine modulates depression-induced behaviour and the expression of Bax mRNA and Bcl-xl mRNA in both hippocampus and myocardium. 21308783

2011
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD N-acetylcysteine attenuates glycerol-induced acute kidney injury by regulating MAPKs and Bcl-2 family proteins. 20037173

2010
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.200 Biomarker RGD A high soy diet reduces programmed cell death and enhances bcl-xL expression in experimental stroke. 17706879

2007
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0028840
Disease: Ocular Hypertension
Ocular Hypertension 		0.200 Biomarker RGD Alteration of retinal intrinsic survival signal and effect of alpha2-adrenergic receptor agonist in the retina of the chronic ocular hypertension rat. 17640403

2007
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0036982
Disease: Shock, Hemorrhagic
Shock, Hemorrhagic 		0.200 Biomarker RGD Hypotensive hemorrhage increases calcium uptake capacity and Bcl-XL content of liver mitochondria. 17224795

2007
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.200 Therapeutic RGD Genetic redox preconditioning differentially modulates AP-1 and NF kappa B responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis. 12668130

2003