Source: INFERRED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. 26502338

2015
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 GeneticVariation GWASCAT A candidate screen of alleles previously associated with other autoimmune diseases suggested five loci (P < 1 x 10(-3)) that may contribute to SLE: IFIH1, CFB, CLEC16A, IL12B and SH2B3. 19838195

2009
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C3888244
Disease: AICARDI-GOUTIERES SYNDROME 7
AICARDI-GOUTIERES SYNDROME 7 		0.610 CausalMutation CLINVAR An extremely severe case of Aicardi-Goutières syndrome 7 with a novel variant in IFIH1. 30965144

2020
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C3888244
Disease: AICARDI-GOUTIERES SYNDROME 7
AICARDI-GOUTIERES SYNDROME 7 		0.610 CausalMutation CLINVAR Further evidence for specific IFIH1 mutation as a cause of Singleton-Merten syndrome with phenotypic heterogeneity. 28319323

2017
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C3888244
Disease: AICARDI-GOUTIERES SYNDROME 7
AICARDI-GOUTIERES SYNDROME 7 		0.610 CausalMutation CLINVAR A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome. 25620204

2015
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C3888244
Disease: AICARDI-GOUTIERES SYNDROME 7
AICARDI-GOUTIERES SYNDROME 7 		0.610 GeneticVariation CLINVAR

Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C4225427
Disease: SINGLETON-MERTEN SYNDROME 1
SINGLETON-MERTEN SYNDROME 1 		0.600 CausalMutation CLINVAR Further evidence for specific IFIH1 mutation as a cause of Singleton-Merten syndrome with phenotypic heterogeneity. 28319323

2017
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C4225427
Disease: SINGLETON-MERTEN SYNDROME 1
SINGLETON-MERTEN SYNDROME 1 		0.600 CausalMutation CLINVAR A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome. 25620204

2015
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C4225427
Disease: SINGLETON-MERTEN SYNDROME 1
SINGLETON-MERTEN SYNDROME 1 		0.600 GeneticVariation CLINVAR

Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.440 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.440 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422

2015
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0162538
Disease: Immunoglobulin A deficiency (disorder)
Immunoglobulin A deficiency (disorder) 		0.400 GeneticVariation GWASCAT Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency. 27723758

2016
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0036572
Disease: Seizures
Seizures 		0.400 Biomarker HPO

Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASCAT Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. 25751624

2015
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASDB A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. 21980299

2011
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393

2011
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASDB Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480

2009
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASCAT Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480

2009
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASCAT Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. 17554260

2007
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.200 GeneticVariation GWASDB Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. 17554260

2007
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.200 Biomarker HPO

Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.160 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0027121
Disease: Myositis
Myositis 		0.160 Biomarker HPO

Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C4049006
Disease: Selective immunoglobulin A deficiency
Selective immunoglobulin A deficiency 		0.130 GeneticVariation GWASCAT Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency. 27723758

2016
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
CUI: C0003864
Disease: Arthritis
Arthritis 		0.120 Biomarker HPO