Source: INFERRED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR Against all odds: blended phenotypes of three single-gene defects. 26813946

2016
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR New insights into thyroglobulin gene: molecular analysis of seven novel mutations associated with goiter and hypothyroidism. 23164529

2013
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR A new compound heterozygous for c.886C>T/c.2206C>T [p.R277X/p.Q717X] mutations in the thyroglobulin gene as a cause of foetal goitrous hypothyroidism. 21128992

2011
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR New insights into thyroglobulin pathophysiology revealed by the study of a family with congenital goiter. 20410234

2010
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR A new case of congenital goiter with hypothyroidism caused by a homozygous p.R277X mutation in the exon 7 of the thyroglobulin gene: a mutational hot spot could explain the recurrence of this mutation. 15769978

2005
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR Two distinct compound heterozygous constellations (R277X/IVS34-1G>C and R277X/R1511X) in the thyroglobulin (TG) gene in affected individuals of a Brazilian kindred with congenital goiter and defective TG synthesis. 14764776

2004
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342194
Disease: Thyroid Dyshormonogenesis 3
Thyroid Dyshormonogenesis 3 		0.700 CausalMutation CLINVAR A premature stopcodon in thyroglobulin messenger RNA results in familial goiter and moderate hypothyroidism. 10404833

1999
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.500 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0018021
Disease: Goiter
Goiter 		0.500 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0013336
Disease: Dwarfism
Dwarfism 		0.410 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.400 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.400 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.400 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.400 CausalMutation CLINVAR

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0018213
Disease: Graves Disease
Graves Disease 		0.200 GeneticVariation GWASDB Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. 23612905

2013
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0018213
Disease: Graves Disease
Graves Disease 		0.200 GeneticVariation GWASCAT Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. 23612905

2013
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0040147
Disease: Thyroiditis
Thyroiditis 		0.200 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.200 CausalMutation CLINVAR

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.200 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0018022
Disease: Endemic goiter
Endemic goiter 		0.170 CausalMutation CLINVAR

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0342162
Disease: Compensated hypothyroidism
Compensated hypothyroidism 		0.110 Biomarker HPO

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0200638
Disease: Eosinophil count procedure
Eosinophil count procedure 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C3150797
Disease: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C4014795
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019