Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0004096
Disease: Asthma
Asthma 		0.260 Biomarker RGD Furthermore, imiquimod (a ligand of TLR7) and TLR3 specific short-hairpin RNA plasmid for RNA interference were administrated, respectively, in vivo to AIPI rats to observe their effects on the disease by assessing various asthmatic parameters. 21364926

2011
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.220 Biomarker RGD Infusion with TLR3 antisense oligodeoxynucleotide (ASO) dose-dependently attenuated CP-induced allodynia. 21342497

2011
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0009319
Disease: Colitis
Colitis 		0.220 Biomarker RGD Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. 20011045

2009
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0031117
Disease: Peripheral Neuropathy
Peripheral Neuropathy 		0.200 Biomarker RGD A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. 20638911

2011
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.200 Biomarker RGD Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. 21355876

2011
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C1335029
Disease: Non-Neoplastic Peripheral Nervous System Disorder
Non-Neoplastic Peripheral Nervous System Disorder 		0.200 Biomarker RGD A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. 20638911

2011
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.200 Biomarker RGD Toll-like receptor 3 activation during pregnancy elicits preeclampsia-like symptoms in rats. 19779466

2009
Entrez Id: 7098
Gene Symbol: TLR3
TLR3
CUI: C0520459
Disease: Necrotizing Enterocolitis
Necrotizing Enterocolitis 		0.200 Biomarker RGD Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis. 19608731

2009