Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C3151071
Disease: COMPLEMENT COMPONENT 3 DEFICIENCY, AUTOSOMAL RECESSIVE
COMPLEMENT COMPONENT 3 DEFICIENCY, AUTOSOMAL RECESSIVE 		disease 0.700 strong 1.000 5 2 1972 2016
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		disease 0.700 limited 1.000 4 2 2007 2020
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C1332655
Disease: Complement component 3 deficiency
Complement component 3 deficiency 		disease 0.630 strong 1.000 1 1 1972 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C2752037
Disease: HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 5
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 5 		disease 0.600 strong 1.000 4 8 2005 2016
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C2931788
Disease: Atypical Hemolytic Uremic Syndrome
Atypical Hemolytic Uremic Syndrome 		disease 0.600 strong 1.000 1 0 2008 2019
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C1969651
Disease: Macular Degeneration, Age-Related, 9
Macular Degeneration, Age-Related, 9 		disease 0.500 None 1.000 2 1 2007 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis 		disease 0.500 None 1.000 1 0 2000 2015
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack 		disease 0.500 None 1.000 1 0 2011 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		disease 0.500 None 1.000 1 0 2011 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome 		disease 0.410 strong 1.000 1 0 2008 2016
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		disease 0.400 None 1.000 1 0 2017 2017
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C4087273
Disease: C3 glomerulopathy
C3 glomerulopathy 		disease 0.330 strong 1.000 1 0 2014 2019
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.330 None 1.000 1 0 2010 2020
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0030809
Disease: Pemphigus Vulgaris
Pemphigus Vulgaris 		disease 0.320 None 1.000 1 0 1977 2019
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		disease 0.310 None 1.000 1 0 2007 2017
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0030807
Disease: Pemphigus
Pemphigus 		disease 0.310 None 1.000 1 0 1977 2019
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0740391
Disease: Middle Cerebral Artery Occlusion
Middle Cerebral Artery Occlusion 		disease 0.310 None 1.000 1 0 2013 2020
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0917805
Disease: Transient Cerebral Ischemia
Transient Cerebral Ischemia 		disease 0.300 None 1.000 1 0 2013 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease 		phenotype 0.300 None 1.000 1 0 2005 2005
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic 		disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0751849
Disease: Right Middle Cerebral Artery Infarction
Right Middle Cerebral Artery Infarction 		phenotype 0.300 None 1.000 1 0 2013 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0751848
Disease: Thrombotic Infarction, Middle Cerebral Artery
Thrombotic Infarction, Middle Cerebral Artery 		phenotype 0.300 None 1.000 1 0 2013 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0751847
Disease: Embolic Infarction, Middle Cerebral Artery
Embolic Infarction, Middle Cerebral Artery 		phenotype 0.300 None 1.000 1 0 2013 2013
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C0920563
Disease: Insulin Sensitivity
Insulin Sensitivity 		phenotype 0.300 None 1.000 1 0 2008 2008
Entrez Id: 718
Gene Symbol: C3
C3 		complement C3 0.445 0.885 0.90
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced 		disease 0.300 None 1.000 1 0 2005 2005