Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C1864827
Disease: HOLOPROSENCEPHALY 5
HOLOPROSENCEPHALY 5 		0.900 Biomarker MGD Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling. 27466203

2016
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C1864827
Disease: HOLOPROSENCEPHALY 5
HOLOPROSENCEPHALY 5 		0.900 Biomarker MGD Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. 18617531

2008
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C1864827
Disease: HOLOPROSENCEPHALY 5
HOLOPROSENCEPHALY 5 		0.900 Biomarker MGD Zic2 is required for neural crest formation and hindbrain patterning during mouse development. 14651926

2003
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C1864827
Disease: HOLOPROSENCEPHALY 5
HOLOPROSENCEPHALY 5 		0.900 Biomarker MGD Zic2 regulates the kinetics of neurulation. 10677508

2000
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.520 Biomarker MGD These results warrant further study of ZIC2 in the pathogenesis of schizophrenia. 22355535

2011