Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute
0.400 Biomarker CTD_human Prognostic significance of CD44v6/v7 in acute promyelocytic leukemia. 23098472

2012

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker CTD_human Prognostic significance of CD44v6/v7 in acute promyelocytic leukemia. 23098472

2012

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker CTD_human CD44-SLC1A2 silencing caused significant reductions in intracellular glutamate concentrations and sensitized SNU16 cells to cisplatin, a commonly used chemotherapeutic agent in gastric cancer. 21471434

2011

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.400 Biomarker CTD_human Considering the overexpression of mRNA, it was tentatively suggested that LY6E, TACSTD1, and CD44 proteins may act as surface markers for sorting pancreatic cancer stem cells with fluorescence-activated cell sorter/magnetic-activated cell sorter. 17446842

2007

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
0.360 Biomarker CTD_human Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties. 17446842

2007

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.320 Biomarker CTD_human CD44-SLC1A2 gene fusions in gastric cancer. 21471434

2011

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia
0.320 Biomarker CTD_human Down-regulation of CD44 contributes to the differentiation of HL-60 cells induced by ATRA or HMBA. 17349212

2007

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia
0.320 Therapeutic CTD_human Down-regulation of CD44 contributes to the differentiation of HL-60 cells induced by ATRA or HMBA. 17349212

2007

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia
0.320 Biomarker CTD_human Finally, A3D8 induces apoptosis in all-trans-retinoic acid-resistant NB4-derived cells and in APL primary blasts, characterizing the A3D8 anti-CD44 mAb as a novel class of apoptosis-inducing agent in APL. 16208414

2005

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia
0.320 Therapeutic CTD_human Finally, A3D8 induces apoptosis in all-trans-retinoic acid-resistant NB4-derived cells and in APL primary blasts, characterizing the A3D8 anti-CD44 mAb as a novel class of apoptosis-inducing agent in APL. 16208414

2005

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0032580
Disease: Adenomatous Polyposis Coli
Adenomatous Polyposis Coli
0.310 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.310 Biomarker CTD_human Repeat oral dose toxicity studies of melamine in rats and monkeys. 23052191

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders
0.310 Biomarker CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338

2006

Entrez Id: 960
Gene Symbol: CD44
CD44
Hereditary Nonpolyposis Colorectal Neoplasms
0.300 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
Hereditary Nonpolyposis Colorectal Cancer
0.300 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C2713442
Disease: Polyposis, Adenomatous Intestinal
Polyposis, Adenomatous Intestinal
0.300 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C2713443
Disease: Familial Intestinal Polyposis
Familial Intestinal Polyposis
0.300 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C4552100
Disease: Lynch Syndrome
Lynch Syndrome
0.300 Biomarker CTD_human Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344

2017

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0011616
Disease: Contact Dermatitis
Contact Dermatitis
0.300 Biomarker CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0162351
Disease: Contact hypersensitivity
Contact hypersensitivity
0.300 Biomarker CTD_human Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay. 25724174

2015

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis
0.300 Biomarker CTD_human The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy. 25133636

2014

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Biomarker CTD_human Repeat oral dose toxicity studies of melamine in rats and monkeys. 23052191

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.300 Biomarker CTD_human Repeat oral dose toxicity studies of melamine in rats and monkeys. 23052191

2013

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0026998
Disease: Acute Myeloid Leukemia, M1
Acute Myeloid Leukemia, M1
0.300 Biomarker CTD_human Prognostic significance of CD44v6/v7 in acute promyelocytic leukemia. 23098472

2012

Entrez Id: 960
Gene Symbol: CD44
CD44
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.300 Biomarker CTD_human Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. 22561518

2012