| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.900 | None | 0.985 | 66 | 4 | 1997 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.800 | None | 0.979 | 47 | 9 | 1998 | 2020 | ||||||||
|
SUFU negative regulator of hedgehog signaling | 0.493 | 0.769 | 1.00 |
|
disease | 0.800 | definitive | 0.950 | 20 | 14 | 1996 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.700 | None | 1.000 | 18 | 5 | 1995 | 2020 | ||||||||
|
smoothened, frizzled class receptor | 0.489 | 0.731 | 4.3E-07 |
|
disease | 0.690 | None | 1.000 | 11 | 2 | 2000 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.630 | strong | 1.000 | 6 | 24 | 2003 | 2018 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.620 | strong | 1.000 | 3 | 2 | 2008 | 2017 | ||||||||
|
patched 2 | 0.563 | 0.692 | 3.4E-16 |
|
disease | 0.610 | moderate | 1.000 | 1 | 1 | 1999 | 1999 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.510 | strong | 0.500 | 2 | 1 | 2003 | 2017 | ||||||||
|
MYCN proto-oncogene, bHLH transcription factor | 0.454 | 0.808 | 0.89 |
|
disease | 0.500 | None | 0.971 | 34 | 2 | 1989 | 2019 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.420 | None | 1.000 | 2 | 2 | 2009 | 2013 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 0.974 | 77 | 0 | 1990 | 2019 | ||||||||
|
orthodenticle homeobox 2 | 0.514 | 0.808 | 0.92 |
|
disease | 0.400 | None | 1.000 | 26 | 0 | 1999 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.400 | None | 1.000 | 15 | 0 | 2005 | 2019 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 14 | 0 | 2008 | 2019 | ||||||||
|
atonal bHLH transcription factor 1 | 0.633 | 0.500 | 1.8E-02 |
|
disease | 0.400 | None | 1.000 | 10 | 0 | 2007 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.400 | None | 0 | 0 | |||||||||||
|
HIC ZBTB transcriptional repressor 1 | 0.522 | 0.615 | 0.13 |
|
disease | 0.390 | None | 1.000 | 9 | 0 | 2002 | 2008 | ||||||||
|
cyclin dependent kinase 6 | 0.471 | 0.731 | 0.98 |
|
disease | 0.380 | None | 1.000 | 10 | 0 | 2005 | 2018 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.370 | None | 1.000 | 8 | 0 | 2001 | 2018 | ||||||||
|
Ras association domain family member 1 | 0.420 | 0.808 | 4.9E-06 |
|
disease | 0.370 | None | 1.000 | 7 | 0 | 2002 | 2011 | ||||||||
|
platelet derived growth factor receptor alpha | 0.415 | 0.808 | 1.00 |
|
disease | 0.360 | None | 1.000 | 7 | 0 | 2001 | 2015 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.350 | None | 1.000 | 6 | 0 | 2009 | 2017 | ||||||||
|
bromodomain containing 4 | 0.446 | 0.885 | 1.00 |
|
disease | 0.340 | None | 1.000 | 5 | 0 | 2013 | 2019 | ||||||||
|
DNA methyltransferase 1 | 0.406 | 0.885 | 1.00 |
|
disease | 0.340 | None | 1.000 | 5 | 0 | 2009 | 2018 |