| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
phenotype | 0.600 | None | 0.958 | 120 | 10 | 2003 | 2020 | ||||||||
|
tachykinin precursor 1 | 0.424 | 0.923 | 0.75 |
|
phenotype | 0.600 | None | 0.960 | 75 | 0 | 1993 | 2020 | ||||||||
|
cannabinoid receptor 1 | 0.446 | 0.808 | 0.51 |
|
phenotype | 0.600 | None | 1.000 | 26 | 2 | 2009 | 2020 | ||||||||
|
transient receptor potential cation channel subfamily A member 1 | 0.546 | 0.846 | 7.2E-35 |
|
phenotype | 0.500 | None | 0.973 | 73 | 2 | 2005 | 2020 | ||||||||
|
oxytocin/neurophysin I prepropeptide | 0.615 | 0.423 | 0.71 |
|
phenotype | 0.500 | None | 1.000 | 3 | 0 | 1984 | 2007 | ||||||||
|
bradykinin receptor B1 | 0.619 | 0.731 | 4.7E-03 |
|
phenotype | 0.500 | None | 1.000 | 2 | 0 | 2007 | 2010 | ||||||||
|
transient receptor potential cation channel subfamily V member 1 | 0.446 | 0.885 | 1.0E-16 |
|
phenotype | 0.400 | None | 0.977 | 177 | 1 | 2000 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.400 | None | 0.960 | 99 | 3 | 2007 | 2020 | ||||||||
|
prepronociceptin | 0.603 | 0.577 | 1.5E-02 |
|
phenotype | 0.400 | None | 1.000 | 28 | 0 | 1998 | 2019 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
phenotype | 0.400 | None | 1.000 | 27 | 0 | 1972 | 2019 | ||||||||
|
GTP cyclohydrolase 1 | 0.511 | 0.846 | 0.90 |
|
phenotype | 0.400 | None | 0.885 | 26 | 0 | 2007 | 2019 | ||||||||
|
kininogen 1 | 0.481 | 0.885 | 3.2E-10 |
|
phenotype | 0.400 | None | 1.000 | 26 | 0 | 1986 | 2020 | ||||||||
|
opioid receptor kappa 1 | 0.555 | 0.615 | 4.1E-05 |
|
phenotype | 0.400 | None | 0.944 | 18 | 5 | 1998 | 2019 | ||||||||
|
hypocretin neuropeptide precursor | 0.500 | 0.808 | 2.9E-02 |
|
phenotype | 0.400 | None | 1.000 | 16 | 0 | 2005 | 2019 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
phenotype | 0.400 | None | 0.933 | 15 | 0 | 2007 | 2020 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
phenotype | 0.390 | None | 1.000 | 10 | 0 | 2000 | 2019 | ||||||||
|
colony stimulating factor 3 | 0.377 | 0.885 | 0.38 |
|
phenotype | 0.380 | None | 1.000 | 11 | 0 | 1995 | 2020 | ||||||||
|
corticotropin releasing hormone | 0.439 | 0.808 | 0.72 |
|
phenotype | 0.380 | None | 1.000 | 9 | 0 | 1997 | 2019 | ||||||||
|
proenkephalin | 0.560 | 0.808 | 2.1E-04 |
|
phenotype | 0.380 | None | 1.000 | 9 | 0 | 1998 | 2017 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
phenotype | 0.360 | None | 1.000 | 7 | 3 | 2005 | 2019 | ||||||||
|
vasoactive intestinal peptide | 0.437 | 0.846 | 4.2E-04 |
|
phenotype | 0.360 | None | 0.857 | 7 | 0 | 1998 | 2019 | ||||||||
|
arginine vasopressin | 0.437 | 0.846 | 7.4E-02 |
|
phenotype | 0.350 | None | 1.000 | 7 | 0 | 1984 | 2019 | ||||||||
|
5-hydroxytryptamine receptor 1A | 0.522 | 0.846 | 0.20 |
|
phenotype | 0.350 | None | 1.000 | 6 | 1 | 2003 | 2018 | ||||||||
|
prodynorphin | 0.535 | 0.577 | 1.7E-04 |
|
phenotype | 0.340 | None | 1.000 | 6 | 0 | 1998 | 2019 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
phenotype | 0.340 | None | 0.600 | 5 | 0 | 1973 | 2019 |