Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.310 None 1.000 2 0 2007 2014
Entrez Id: 6319
Gene Symbol: SCD
SCD
stearoyl-CoA desaturase 0.490 0.808 0.97
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.310 None 1.000 2 0 2007 2014
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
thyroid stimulating hormone receptor 0.486 0.808 3.0E-15
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.100 None 0.957 69 2 1993 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.100 None 1.000 23 2 1996 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.100 None 0.944 18 0 2001 2019
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
cytotoxic T-lymphocyte associated protein 4 0.369 0.923 0.94
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.100 None 0.933 15 3 2000 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.090 None 1.000 9 0 2004 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.090 None 0.889 9 0 2012 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
insulin like growth factor 1 receptor 0.399 0.885 0.97
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.090 None 1.000 9 0 2004 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.070 None 1.000 7 1 1996 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.070 None 1.000 7 0 1991 2019
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
microRNA 146a 0.398 0.885
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.070 None 1.000 7 0 2014 2019
Entrez Id: 958
Gene Symbol: CD40
CD40
CD40 molecule 0.396 0.846 0.85
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.070 None 1.000 7 1 1998 2018
Entrez Id: 947
Gene Symbol: CD34
CD34
CD34 molecule 0.368 0.808 5.0E-06
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.060 None 1.000 6 0 2013 2019
Entrez Id: 7173
Gene Symbol: TPO
TPO
thyroid peroxidase 0.455 0.846 1.8E-21
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.060 None 0.833 6 1 2006 2020
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.060 None 1.000 6 0 2010 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.050 None 1.000 5 0 2002 2019
Entrez Id: 7038
Gene Symbol: TG
TG
thyroglobulin 0.480 0.808 2.9E-59
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.050 None 1.000 5 0 1989 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.050 None 1.000 5 0 2016 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.050 None 1.000 5 1 2003 2020
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
keratin 20 0.388 0.846 9.1E-11
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.040 None 1.000 4 0 2017 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.040 None 1.000 4 0 2008 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.040 None 1.000 4 0 2014 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.040 None 0.750 4 0 1997 2009
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
membrane spanning 4-domains A1 0.411 0.846 5.1E-05
CUI: C0339143
Disease: Thyroid associated opthalmopathies
Thyroid associated opthalmopathies
disease 0.040 None 1.000 4 0 2017 2019