| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.700 | strong | 0.964 | 83 | 10 | 1993 | 2020 | ||||||||
|
triggering receptor expressed on myeloid cells 2 | 0.519 | 0.769 | 3.3E-09 |
|
disease | 0.700 | strong | 1.000 | 19 | 5 | 2005 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.992 | 127 | 13 | 1995 | 2020 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.500 | strong | 0.958 | 48 | 4 | 1991 | 2019 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.500 | None | 1.000 | 46 | 4 | 2006 | 2019 | ||||||||
|
notch receptor 3 | 0.435 | 0.808 | 0.41 |
|
disease | 0.500 | strong | 1.000 | 20 | 1 | 1996 | 2017 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.500 | strong | 1.000 | 17 | 3 | 1997 | 2018 | ||||||||
|
cystatin C | 0.436 | 0.808 | 3.9E-03 |
|
disease | 0.460 | limited | 1.000 | 6 | 0 | 1996 | 2019 | ||||||||
|
DNA methyltransferase 1 | 0.406 | 0.885 | 1.00 |
|
disease | 0.450 | None | 1.000 | 5 | 0 | 2011 | 2015 | ||||||||
|
ceruloplasmin | 0.466 | 0.846 | 4.2E-10 |
|
disease | 0.410 | None | 1.000 | 2 | 0 | 2003 | 2015 | ||||||||
|
HtrA serine peptidase 1 | 0.532 | 0.692 | 4.9E-04 |
|
disease | 0.400 | strong | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
FUS RNA binding protein | 0.470 | 0.846 | 1.00 |
|
disease | 0.380 | None | 1.000 | 9 | 0 | 2009 | 2017 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
disease | 0.360 | None | 1.000 | 7 | 1 | 1992 | 2019 | ||||||||
|
transmembrane immune signaling adaptor TYROBP | 0.573 | 0.769 | 0.20 |
|
disease | 0.360 | strong | 1.000 | 7 | 0 | 2000 | 2018 | ||||||||
|
colony stimulating factor 1 receptor | 0.448 | 0.808 | 0.13 |
|
disease | 0.330 | strong | 1.000 | 4 | 0 | 2013 | 2019 | ||||||||
|
collagen type IV alpha 1 chain | 0.484 | 0.731 | 1.00 |
|
disease | 0.310 | strong | 1.000 | 2 | 0 | 2007 | 2016 | ||||||||
|
solute carrier family 9 member A8 | 0.736 | 0.500 | 2.9E-10 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.916 | 605 | 6 | 1994 | 2020 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.200 | None | 0.986 | 70 | 4 | 1998 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.200 | None | 0.983 | 58 | 22 | 1990 | 2019 | ||||||||
|
C9orf72-SMCR8 complex subunit | 0.496 | 0.769 | 1.1E-06 |
|
disease | 0.200 | None | 0.941 | 34 | 0 | 2012 | 2020 | ||||||||
|
integral membrane protein 2B | 0.617 | 0.654 | 0.63 |
|
disease | 0.200 | None | 0.966 | 29 | 0 | 1999 | 2019 | ||||||||
|
valosin containing protein | 0.469 | 0.923 | 1.00 |
|
disease | 0.200 | None | 0.958 | 24 | 3 | 2005 | 2019 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.200 | None | 0.812 | 16 | 2 | 2005 | 2019 | ||||||||
|
charged multivesicular body protein 2B | 0.543 | 0.731 | 4.6E-06 |
|
disease | 0.190 | None | 1.000 | 9 | 0 | 2005 | 2016 |