Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
thyroid stimulating hormone receptor | 0.486 | 0.808 | 3.0E-15 |
|
disease | 0.600 | None | 0.964 | 27 | 0 | 1992 | 2019 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
disease | 0.370 | None | 1.000 | 7 | 0 | 1991 | 2017 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.360 | None | 1.000 | 6 | 3 | 2003 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.360 | None | 1.000 | 6 | 0 | 2004 | 2015 | ||||||||
|
solute carrier family 5 member 5 | 0.499 | 0.769 | 2.9E-03 |
|
disease | 0.340 | None | 1.000 | 4 | 0 | 1998 | 2007 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.340 | None | 1.000 | 4 | 0 | 2001 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2005 | 2012 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 1988 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2006 | 2012 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2015 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2015 | 2017 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.140 | None | 1.000 | 4 | 0 | 2007 | 2012 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2005 | 2007 | ||||||||
|
protein kinase cAMP-dependent type I regulatory subunit alpha | 0.401 | 0.846 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
disease | 0.110 | None | 1.000 | 1 | 1 | 2017 | 2017 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
galectin 3 | 0.392 | 0.846 | 2.3E-05 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2003 | ||||||||
|
coiled-coil domain containing 6 | 0.517 | 0.808 | 0.58 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1991 | 2017 | ||||||||
|
taste 2 receptor member 38 | 0.531 | 0.808 | 0.13 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1991 | 2017 | ||||||||
|
paired box 8 | 0.477 | 0.731 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2012 | ||||||||
|
coagulation factor IX | 0.465 | 0.885 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1991 | 2017 | ||||||||
|
eukaryotic translation initiation factor 1A X-linked | 0.716 | 0.231 | 0.91 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2018 | 2019 | ||||||||
|
THADA armadillo repeat containing | 0.686 | 0.500 | 4.6E-41 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 2003 | 2014 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1991 | 2017 | ||||||||
|
enhancer of zeste 1 polycomb repressive complex 2 subunit | 0.663 | 0.577 | 4.3E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2016 | 2018 |