|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Identification of two novel mutations in RASGRP2 affecting platelet CalDAG-GEFI expression and function in patients with bleeding diathesis.
|
28762304 |
2018 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Expanded repertoire of RASGRP2 variants responsible for platelet dysfunction and severe bleeding.
|
28637664 |
2017 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction.
|
27235135 |
2016 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Mice Expressing Low Levels of CalDAG-GEFI Exhibit Markedly Impaired Platelet Activation With Minor Impact on Hemostasis.
|
27417588 |
2016 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Human CalDAG-GEFI deficiency increases bleeding and delays αIIbβ3 activation.
|
27663674 |
2016 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding.
|
24958846 |
2014 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets.
|
17576779 |
2007 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation.
|
15334074 |
2004 |
|
| Entrez Id: |
10235 |
| Gene Symbol: |
RASGRP2 |
RASGRP2
|
BLEEDING DISORDER, PLATELET-TYPE, 18
|
0.700 |
Biomarker |
CLINGEN |
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.
|
9789079 |
1998 |