| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
SURF1 cytochrome c oxidase assembly factor | 0.578 | 0.654 | 1.6E-13 |
|
disease | 1.000 | definitive | 0.987 | 22 | 17 | 1998 | 2018 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit S4 | 0.587 | 0.808 | 3.1E-04 |
|
disease | 1.000 | definitive | 0.968 | 5 | 4 | 2001 | 2019 | ||||||||
|
cytochrome c oxidase assembly homolog COX15 | 0.638 | 0.538 | 1.1E-13 |
|
disease | 0.740 | limited | 1.000 | 4 | 1 | 2002 | 2016 | ||||||||
|
succinate dehydrogenase complex flavoprotein subunit A | 0.517 | 0.731 | 2.6E-10 |
|
disease | 0.730 | moderate | 0.917 | 0 | 1 | 1992 | 2017 | ||||||||
|
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | 0.534 | 0.808 | 4.7E-13 |
|
disease | 0.700 | limited | 1.000 | 5 | 3 | 1998 | 2017 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit S8 | 0.636 | 0.538 | 0.17 |
|
disease | 0.630 | moderate | 1.000 | 0 | 3 | 1998 | 2018 | ||||||||
|
ATP synthase F0 subunit 6 | 0.541 | 0.731 |
|
disease | 0.500 | None | 1.000 | 21 | 11 | 1990 | 2020 | |||||||||
|
NADH dehydrogenase, subunit 3 (complex I) | 0.604 | 0.654 |
|
disease | 0.490 | None | 1.000 | 11 | 16 | 2001 | 2019 | |||||||||
|
NADH dehydrogenase, subunit 5 (complex I) | 0.531 | 0.769 |
|
disease | 0.470 | None | 1.000 | 11 | 8 | 1997 | 2019 | |||||||||
|
NADH dehydrogenase, subunit 6 (complex I) | 0.544 | 0.808 |
|
disease | 0.470 | None | 1.000 | 9 | 5 | 1994 | 2019 | |||||||||
|
enoyl-CoA hydratase, short chain 1 | 0.601 | 0.654 | 8.8E-04 |
|
disease | 0.440 | None | 1.000 | 0 | 2 | 2014 | 2019 | ||||||||
|
NADH:ubiquinone oxidoreductase complex assembly factor 6 | 0.659 | 0.615 | 9.1E-08 |
|
disease | 0.440 | strong | 1.000 | 0 | 1 | 2008 | 2019 | ||||||||
|
isoleucyl-tRNA synthetase 2, mitochondrial | 0.590 | 0.654 | 8.1E-02 |
|
disease | 0.430 | limited | 1.000 | 1 | 1 | 2014 | 2018 | ||||||||
|
NADH:ubiquinone oxidoreductase complex assembly factor 2 | 0.641 | 0.577 | 2.1E-06 |
|
disease | 0.420 | None | 1.000 | 2 | 2 | 2005 | 2016 | ||||||||
|
FAD dependent oxidoreductase domain containing 1 | 0.633 | 0.462 | 2.0E-16 |
|
disease | 0.420 | moderate | 1.000 | 0 | 1 | 2010 | 2019 | ||||||||
|
NADH dehydrogenase, subunit 4 (complex I) | 0.546 | 0.769 |
|
disease | 0.150 | None | 1.000 | 2 | 15 | 2003 | 2017 | |||||||||
|
mitochondrial methionyl-tRNA formyltransferase | 0.595 | 0.808 | 1.5E-07 |
|
disease | 0.140 | None | 1.000 | 2 | 1 | 2011 | 2017 | ||||||||
|
NADH dehydrogenase, subunit 1 (complex I) | 0.522 | 0.769 |
|
disease | 0.130 | None | 1.000 | 6 | 8 | 2002 | 2014 | |||||||||
|
tRNA | 0.563 | 0.731 |
|
disease | 0.120 | None | 1.000 | 3 | 2 | 1997 | 2015 | |||||||||
|
cytochrome c oxidase III | 0.546 | 0.808 |
|
disease | 0.120 | None | 1.000 | 2 | 16 | 2000 | 2013 | |||||||||
|
mitochondrial ribosomal protein S34 | 0.722 | 0.346 | 2.6E-03 |
|
disease | 0.110 | None | 1.000 | 1 | 2 | 1986 | 2017 | ||||||||
|
MTND2 | 0.601 | 0.615 |
|
disease | 0.110 | None | 1.000 | 0 | 8 | 2007 | 2007 | |||||||||
|
cutC copper transporter | 0.861 | 0.192 | 6.1E-04 |
|
disease | 0.100 | None | 1.000 | 4 | 1 | 2005 | 2016 | ||||||||
|
tRNA | 0.608 | 0.577 |
|
disease | 0.100 | None | 1.000 | 3 | 2 | 1991 | 2000 | |||||||||
|
tRNA | 0.670 | 0.423 |
|
disease | 0.100 | None | 1.000 | 2 | 2 | 1997 | 2002 |